Advanced Research Center for Innovations in Next-Generation Medicine (INGEM)

2024

Current treatment strategies for ovarian cancer in the East Asian Gynecologic Oncology Trial Group (EAGOT)

Kobayashi, Y., Shimada, M., Tamate, M., Cho, H. W., Zhu, J., Chou, H. H., Kajiyama, H., Okamoto, A., Aoki, D., Kang, S., Lee, J. W., Kim, J. W., Kim, J. H., Lin, Z., Liu, J., Wu, X., Lai, H. C., Chang, T. C., Lai, C. H. & Kim, Y. M. & 1 others, Enomoto, T., 2024 May, In: Journal of Gynecologic Oncology. 35, 3, e87.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Citations (Scopus)

Role of NRF2 in Pathogenesis of Alzheimer’s Disease

Chu, C. T., Uruno, A., Katsuoka, F. & Yamamoto, M., 2024 Dec, In: Antioxidants. 13, 12, 1529.

Research output: Contribution to journal › Review article › peer-review

Open Access

Two-stage strategy using denoising autoencoders for robust reference-free genotype imputation with missing input genotypes

Kojima, K., Tadaka, S., Okamura, Y. & Kinoshita, K., 2024 Oct, In: Journal of Human Genetics. 69, 10, p. 511-518 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2023

Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project

Kobayashi, T., Kobayashi, M., Minegishi, N., Kikuya, M., Obara, T., Ishikuro, M., Yamanaka, C., Onuma, T., Murakami, K., Ueno, F., Noda, A., Uruno, A., Sugawara, J., Suzuki, K., Kodama, E. N., Hamanaka, Y., Tsuchiya, N., Kogure, M., Nakaya, N. & Taira, M. & 16 others, Sakurai-Yageta, M., Tamahara, T., Kawashima, J., Goto, M., Otsuki, A., Shimizu, R., Ogishima, S., Hashizume, H., Nagami, F., Nakamura, T., Hozawa, A., Kobayashi, T., Fuse, N., Kuriyama, S., Kure, S. & Yamamoto, M., 2023, In: Tohoku Journal of Experimental Medicine. 259, 2, p. 93-105 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Citation (Scopus)

2022

Novel NRF2-activated cancer treatments utilizing synthetic lethality

Baird, L., Kensler, T. W. & Yamamoto, M., 2022 Dec, In: IUBMB Life. 74, 12, p. 1209-1231 23 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Citations (Scopus)

2021

GA4GH: International policies and standards for data sharing across genomic research and healthcare

Rehm, H. L., Page, A. J. H., Smith, L., Adams, J. B., Alterovitz, G., Babb, L. J., Barkley, M. P., Baudis, M., Beauvais, M. J. S., Beck, T., Beckmann, J. S., Beltran, S., Bernick, D., Bernier, A., Bonfield, J. K., Boughtwood, T. F., Bourque, G., Bowers, S. R., Brookes, A. J. & Brudno, M. & 182 others, Brush, M. H., Bujold, D., Burdett, T., Buske, O. J., Cabili, M. N., Cameron, D. L., Carroll, R. J., Casas-Silva, E., Chakravarty, D., Chaudhari, B. P., Chen, S. H., Cherry, J. M., Chung, J., Cline, M., Clissold, H. L., Cook-Deegan, R. M., Courtot, M., Cunningham, F., Cupak, M., Davies, R. M., Denisko, D., Doerr, M. J., Dolman, L. I., Dove, E. S., Dursi, L. J., Dyke, S. O. M., Eddy, J. A., Eilbeck, K., Ellrott, K. P., Fairley, S., Fakhro, K. A., Firth, H. V., Fitzsimons, M. S., Fiume, M., Flicek, P., Fore, I. M., Freeberg, M. A., Freimuth, R. R., Fromont, L. A., Fuerth, J., Gaff, C. L., Gan, W., Ghanaim, E. M., Glazer, D., Green, R. C., Griffith, M., Griffith, O. L., Grossman, R. L., Groza, T., Guidry Auvil, J. M., Guigó, R., Gupta, D., Haendel, M. A., Hamosh, A., Hansen, D. P., Hart, R. K., Hartley, D. M., Haussler, D., Hendricks-Sturrup, R. M., Ho, C. W. L., Hobb, A. E., Hoffman, M. M., Hofmann, O. M., Holub, P., Hsu, J. S., Hubaux, J. P., Hunt, S. E., Husami, A., Jacobsen, J. O., Jamuar, S. S., Janes, E. L., Jeanson, F., Jené, A., Johns, A. L., Joly, Y., Jones, S. J. M., Kanitz, A., Kato, K., Keane, T. M., Kekesi-Lafrance, K., Kelleher, J., Kerry, G., Khor, S. S., Knoppers, B. M., Konopko, M. A., Kosaki, K., Kuba, M., Lawson, J., Leinonen, R., Li, S., Lin, M. F., Linden, M., Liu, X., Liyanage, I. U., Lopez, J., Lucassen, A. M., Lukowski, M., Mann, A. L., Marshall, J., Mattioni, M., Metke-Jimenez, A., Middleton, A., Milne, R. J., Molnár-Gábor, F., Mulder, N., Munoz-Torres, M. C., Nag, R., Nakagawa, H., Nasir, J., Navarro, A., Nelson, T. H., Niewielska, A., Nisselle, A., Niu, J., Nyrönen, T. H., O'Connor, B. D., Oesterle, S., Ogishima, S., Ota Wang, V., Paglione, L. A. D., Palumbo, E., Parkinson, H. E., Philippakis, A. A., Pizarro, A. D., Prlic, A., Rambla, J., Rendon, A., Rider, R. A., Robinson, P. N., Rodarmer, K. W., Rodriguez, L. L., Rubin, A. F., Rueda, M., Rushton, G. A., Ryan, R. S., Saunders, G. I., Schuilenburg, H., Schwede, T., Scollen, S., Senf, A., Sheffield, N. C., Skantharajah, N., Smith, A. V., Sofia, H. J., Spalding, D., Spurdle, A. B., Stark, Z., Stein, L. D., Suematsu, M., Tan, P., Tedds, J. A., Thomson, A. A., Thorogood, A., Tickle, T. L., Tokunaga, K., Törnroos, J., Torrents, D., Upchurch, S., Valencia, A., Guimera, R. V., Vamathevan, J., Varma, S., Vears, D. F., Viner, C., Voisin, C., Wagner, A. H., Wallace, S. E., Walsh, B. P., Williams, M. S., Winkler, E. C., Wold, B. J., Wood, G. M., Woolley, J. P., Yamasaki, C., Yates, A. D., Yung, C. K., Zass, L. J., Zaytseva, K., Zhang, J., Goodhand, P., North, K. & Birney, E., 2021 Nov 10, In: Cell Genomics. 1, 2, 100029.

Research output: Contribution to journal › Review article › peer-review

Open Access

128 Citations (Scopus)

Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics

Saigusa, D., Matsukawa, N., Hishinuma, E. & Koshiba, S., 2021 Apr, In: Drug Metabolism and Pharmacokinetics. 37, 100373.

Research output: Contribution to journal › Review article › peer-review

Open Access

43 Citations (Scopus)

2020

In vitro assessment of fluoropyrimidine-metabolizing enzymes: Dihydropyrimidine dehydrogenase, dihydropyrimidinase, and β-ureidopropionase

Hishinuma, E., Rico, E. G. & Hiratsuka, M., 2020 Aug, In: Journal of Clinical Medicine. 9, 8, p. 1-21 21 p., 2342.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Citations (Scopus)

Management of Stage IIB Cervical Cancer: an Overview of the Current Evidence

Matsuzaki, S., Klar, M., Mikami, M., Shimada, M., Grubbs, B. H., Fujiwara, K., Roman, L. D. & Matsuo, K., 2020 Mar 1, In: Current Oncology Reports. 22, 3, 28.

Research output: Contribution to journal › Review article › peer-review

Open Access

14 Citations (Scopus)

2019

Perioperative treatments for stage IB-IIB uterine cervical cancer

Shimada, M., Tokunaga, H., Kobayashi, H., Ishikawa, M. & Yaegashi, N., 2019 Dec 23, In: Japanese Journal of Clinical Oncology. 50, 2, p. 99-103 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Citations (Scopus)

Sentinel node navigation surgery in cervical and endometrial cancer: A review

Niikura, H., Tsuji, K., Tokunaga, H., Shimada, M., Ishikawa, M. & Yaegashi, N., 2019 May 29, In: Japanese Journal of Clinical Oncology. 49, 6, p. 495-500 6 p.

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

TNM classification of gynaecological malignant tumours, eighth edition: Changes between the seventh and eighth editions

Tokunaga, H., Shimada, M., Ishikawa, M. & Yaegashi, N., 2019 Mar 28, In: Japanese Journal of Clinical Oncology. 49, 4, p. 311-320 10 p.

Research output: Contribution to journal › Review article › peer-review

22 Citations (Scopus)

2018

Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project

Koshiba, S., Motoike, I., Saigusa, D., Inoue, J., Shirota, M., Katoh, Y., Katsuoka, F., Danjoh, I., Hozawa, A., Kuriyama, S., Minegishi, N., Nagasaki, M., Takai-Igarashi, T., Ogishima, S., Fuse, N., Kure, S., Tamiya, G., Tanabe, O., Yasuda, J. & Kinoshita, K. & 1 others, Yamamoto, M., 2018 Jun, In: Genes to Cells. 23, 6, p. 406-417 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

40 Citations (Scopus)

2017

Contributions of the Japanese Gynecologic Oncology Group (JGOG) in Improving the Quality of Life in Women With Gynecological Malignancies

Futagami, M., Yokoyama, Y., Shimada, M., Sato, S., Miyagi, E., Tozawa-Ono, A., Suzuki, N., Fujimura, M., Aoki, Y., Sagae, S. & Sugiyama, T., 2017 Apr 1, In: Current Oncology Reports. 19, 4, 25.

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Update on rare epithelial ovarian cancers: Based on the rare ovarian tumors young investigator conference

Jang, J. Y. A., Yanaihara, N., Pujade-Lauraine, E., Mikami, Y., Oda, K., Bookman, M., Ledermann, J., Shimada, M., Kiyokawa, T., Kim, B. G., Matsumura, N., Kaku, T., Kuroda, T., Nagayoshi, Y., Kawabata, A., Iida, Y., Kim, J. W., Quinn, M. & Okamoto, A., 2017, In: Journal of Gynecologic Oncology. 28, 4, e54.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Citations (Scopus)

2016

Small Maf proteins (MafF, MafG, MafK): History, structure and function

Katsuoka, F. & Yamamoto, M., 2016 Jul 25, In: Gene. 586, 2, p. 197-205 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

179 Citations (Scopus)

2015

Implementation of linked data in the life sciences at BioHackathon 2011

Aoki-Kinoshita, K. F., Kinjo, A. R., Morita, M., Igarashi, Y., Chen, Y. A., Shigemoto, Y., Fujisawa, T., Akune, Y., Katoda, T., Kokubu, A., Mori, T., Nakao, M., Kawashima, S., Okamoto, S., Katayama, T. & Ogishima, S., 2015 Jan 7, In: Journal of Biomedical Semantics. 6, 1, 3.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Citations (Scopus)

2014

BioHackathon series in 2011 and 2012: Penetration of ontology and linked data in life science domains

Katayama, T., Wilkinson, M. D., Aoki-Kinoshita, K. F., Kawashima, S., Yamamoto, Y., Yamaguchi, A., Okamoto, S., Kawano, S., Kim, J. D., Wang, Y., Wu, H., Kano, Y., Ono, H., Bono, H., Kocbek, S., Aerts, J., Akune, Y., Antezana, E., Arakawa, K. & Aranda, B. & 65 others, Baran, J., Bolleman, J., Bonnal, R. J. P., Buttigieg, P. L., Campbell, M. P., Chen, Y. A., Chiba, H., Cock, P. J. A., Cohen, K. B., Constantin, A., Duck, G., Dumontier, M., Fujisawa, T., Fujiwara, T., Goto, N., Hoehndorf, R., Igarashi, Y., Itaya, H., Ito, M., Iwasaki, W., Kalaš, M., Katoda, T., Kim, T., Kokubu, A., Komiyama, Y., Kotera, M., Laibe, C., Lapp, H., Lütteke, T., Marshall, M. S., Mori, T., Mori, H., Morita, M., Murakami, K., Nakao, M., Narimatsu, H., Nishide, H., Nishimura, Y., Nystrom-Persson, J., Ogishima, S., Okamura, Y., Okuda, S., Oshita, K., Packer, N. H., Prins, P., Ranzinger, R., Rocca-Serra, P., Sansone, S., Sawaki, H., Shin, S. H., Splendiani, A., Strozzi, F., Tadaka, S., Toukach, P., Uchiyama, I., Umezaki, M., Vos, R., Whetzel, P. L., Yamada, I., Yamasaki, C., Yamashita, R., York, W. S., Zmasek, C. M., Kawamoto, S. & Takagi, T., 2014, In: Journal of Biomedical Semantics. 5, 1, 5.

Research output: Contribution to journal › Review article › peer-review

Open Access

36 Citations (Scopus)

Monitoring Keap1-Nrf2 interactions in single live cells

Baird, L., Swift, S., Llères, D. & Dinkova-Kostova, A. T., 2014, In: Biotechnology Advances. 32, 6, p. 1133-1144 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

135 Citations (Scopus)

2013

Nedaplatin: A cisplatin derivative in cancer chemotherapy

Shimada, M., Itamochi, H. & Kigawa, J., 2013 May 7, In: Cancer Management and Research. 5, 1, p. 67-76 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

108 Citations (Scopus)

The 3rd DBCLS BioHackathon: Improving life science data integration with Semantic Web technologies

Katayama, T., Wilkinson, M. D., Micklem, G., Kawashima, S., Yamaguchi, A., Nakao, M., Yamamoto, Y., Okamoto, S., Oouchida, K., Chun, H. W., Aerts, J., Afzal, H., Antezana, E., Arakawa, K., Aranda, B., Belleau, F., Bolleman, J., Bonnal, R. J. P., Chapman, B. & Cock, P. J. A. & 46 others, Eriksson, T., Gordon, P. M. K., Goto, N., Hayashi, K., Horn, H., Ishiwata, R., Kaminuma, E., Kasprzyk, A., Kawaji, H., Kido, N., Kim, Y. J., Kinjo, A. R., Konishi, F., Kwon, K. H., Labarga, A., Lamprecht, A. L., Lin, Y., Lindenbaum, P., McCarthy, L., Morita, H., Murakami, K., Nagao, K., Nishida, K., Nishimura, K., Nishizawa, T., Ogishima, S., Ono, K., Oshita, K., Park, K. J., Prins, P., Saito, T. L., Samwald, M., Satagopam, V. P., Shigemoto, Y., Smith, R., Splendiani, A., Sugawara, H., Taylor, J., Vos, R. A., Withers, D., Yamasaki, C., Zmasek, C. M., Kawamoto, S., Okubo, K., Asai, K. & Takagi, T., 2013 Feb 11, In: Journal of Biomedical Semantics. 4, 1, 6.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Citations (Scopus)

2011

The cytoprotective role of the Keap1-Nrf2 pathway

Baird, L. & Dinkova-Kostova, A. T., 2011 Apr, In: Archives of Toxicology. 85, 4, p. 241-272 32 p.

Research output: Contribution to journal › Review article › peer-review

856 Citations (Scopus)

2007

Hypoxia and heme oxygenases: Oxygen sensing and regulation of expression

Shibahara, S., Han, F., Li, B. & Takeda, K., 2007 Oct 1, In: Antioxidants and Redox Signaling. 9, 12, p. 2209-2225 17 p.

Research output: Contribution to journal › Review article › peer-review

60 Citations (Scopus)

2004

Lymphadenectomy for cervical cancer: indications and limits

Shimada, M., Kigawa, J. & Terakawa, N., 2004 Oct, In: Nippon rinsho. Japanese journal of clinical medicine. 62 Suppl 10, p. 219-221 3 p.

Research output: Contribution to journal › Review article › peer-review

2002

High-throughput NMR structure determination: The present and the future

Hatanaka, H., Koshiba, S., Kikuchi, J., Kigawa, T. & Yokoyama, S., 2002 Jun, In: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 47, 8 Suppl, p. 1038-1044 7 p.

Research output: Contribution to journal › Review article › peer-review

Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

Motohashi, H., O'Connor, T., Katsuoka, F., Engel, J. D. & Yamamoto, M., 2002 Jul 10, In: Gene. 294, 1-2, p. 1-12 12 p.

Research output: Contribution to journal › Review article › peer-review

408 Citations (Scopus)

2001

p53 gene status and chemosensitivity in ovarian cancer.

Kigawa, J., Sato, S., Shimada, M., Takahashi, M., Itamochi, H., Kanamori, Y. & Terakawa, N., 2001, In: Human Cell. 14, 3, p. 165-171 7 p.

Research output: Contribution to journal › Review article › peer-review

60 Citations (Scopus)

1999

Structural biology for PH and other domains involved in signal transduction

Koshiba, S. & Yokoyama, S., 1999 Mar, In: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 44, 4 Suppl, p. 368-379 12 p.

Research output: Contribution to journal › Review article › peer-review

Advanced Research Center for Innovations in Next-Generation Medicine (INGEM)

Research output

Search results