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Nobuyuki Takahashi

Professor

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1993 …2022

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  • 2022

    Methylglyoxal Induces Inflammation, Metabolic Modulation and Oxidative Stress in Myoblast Cells

    Todoriki, S., Hosoda, Y., Yamamoto, T., Watanabe, M., Sekimoto, A., Sato, H., Mori, T., Miyazaki, M., Takahashi, N. & Sato, E., 2022 Apr, In: Toxins. 14, 4, 263.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Citations (Scopus)
  • 2021

    Effect of uremic toxins on hippocampal cell damage: analysis in vitro and in rat model of chronic kidney disease

    Watanabe, K., Sato, E., Mishima, E., Watanabe, M., Abe, T., Takahashi, N. & Nakayama, M., 2021 Feb, In: Heliyon. 7, 2, e06221.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6 Citations (Scopus)

  • Lack of Endothelial Nitric Oxide Synthase Accelerates Ectopic Calcification in Uremic Mice Fed an Adenine and High Phosphorus Diet

    Oe, Y., Mitsui, S., Sato, E., Shibata, N., Kisu, K., Sekimoto, A., Miyazaki, M., Sato, H., Ito, S. & Takahashi, N., 2021 Feb, In: American Journal of Pathology. 191, 2, p. 283-293 11 p.

    Research output: Contribution to journal › Article › peer-review

    6 Citations (Scopus)

  • Myeloid cell-derived coagulation tissue factor is associated with renal tubular damage in mice fed an adenine diet

    Yamakage, S., Oe, Y., Sato, E., Okamoto, K., Sekimoto, A., Kumakura, S., Sato, H., Yoshida, M., Nagasawa, T., Miyazaki, M., Ito, S., Mackman, N. & Takahashi, N., 2021 Dec, In: Scientific reports. 11, 1, 12159.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Citation (Scopus)

  • Nicotinamide Attenuates the Progression of Renal Failure in a Mouse Model of Adenine-Induced Chronic Kidney Disease

    Kumakura, S., Sato, E., Sekimoto, A., Hashizume, Y., Yamakage, S., Miyazaki, M., Ito, S., Harigae, H. & Takahashi, N., 2021 Jan, In: Toxins. 13, 1, 50.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Citations (Scopus)

  • Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition

    Handa, T., Mori, K. P., Ishii, A., Ohno, S., Kanai, Y., Watanabe-Takano, H., Yasoda, A., Kuwabara, T., Takahashi, N., Mochizuki, N., Mukoyama, M., Yanagita, M. & Yokoi, H., 2021 Dec, In: Scientific reports. 11, 1, 21835.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Renal function in Japanese HIV-1-positive patients who switch to tenofovir alafenamide fumarate after long-term tenofovir disoproxil fumarate: a single-center observational study

    Abe, K., Obara, T., Kamio, S., Kondo, A., Imamura, J., Goto, T., Ito, T., Sato, H. & Takahashi, N., 2021 Dec, In: AIDS Research and Therapy. 18, 1, 94.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Citations (Scopus)
  • 2020

    Dual blockade of protease-activated receptor 1 and 2 additively ameliorates diabetic kidney disease

    Mitsui, S., Oe, Y., Sekimoto, A., Sato, E., Hashizume, Y., Yamakage, S., Kumakura, S., Sato, H., Ito, S. & Takahashi, N., 2020 May, In: American Journal of Physiology - Renal Physiology. 318, 5, p. F1067-F1073

    Research output: Contribution to journal › Article › peer-review

    7 Citations (Scopus)

  • Effects of the oral adsorbent AST-120 on fecal p-cresol and indole levels and on the gut microbiota composition

    Sato, E., Hosomi, K., Sekimoto, A., Mishima, E., Oe, Y., Saigusa, D., Ito, S., Abe, T., Sato, H., Kunisawa, J., Niwa, T. & Takahashi, N., 2020 May 7, In: Biochemical and biophysical research communications. 525, 3, p. 773-779 7 p.

    Research output: Contribution to journal › Article › peer-review

    10 Citations (Scopus)

  • Metabolomics of a mouse model of preeclampsia induced by overexpressing soluble fms-like tyrosine kinase 1

    Sato, E., Tsunokuni, Y., Kaneko, M., Saigusa, D., Saito, R., Shimma, S., Sekimoto, A., Kawana, Y., Oe, Y., Ito, S., Sato, H. & Takahashi, N., 2020 Jul 5, In: Biochemical and biophysical research communications. 527, 4, p. 1064-1071 8 p.

    Research output: Contribution to journal › Article › peer-review

    6 Citations (Scopus)

  • Oral high dose vitamin B12 decreases renal superoxide and post-ischemia/reperfusion injury in mice

    Li, F., Bahnson, E. M., Wilder, J., Siletzky, R., Hagaman, J., Nickekeit, V., Hiller, S., Ayesha, A., Feng, L., Levine, J. S., Takahashi, N. & Maeda-Smithies, N., 2020 May, In: Redox Biology. 32, 101504.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Citations (Scopus)

  • Protease-activated receptor 2 contributes to placental development and fetal growth in mice

    Yamakage, S., Oe, Y., Sekimoto, A., Obata, H., Yasuta, M., Sato, E., Kumakura, S., Sato, H., Sugawara, J., Ito, S. & Takahashi, N., 2020 Sept, In: Thrombosis Research. 193, p. 173-179 7 p.

    Research output: Contribution to journal › Article › peer-review

    2 Citations (Scopus)

  • Tadalafil alleviates preeclampsia and fetal growth restriction in RUPP model of preeclampsia in mice

    Sekimoto, A., Tanaka, K., Hashizume, Y., Sato, E., Sato, H., Ikeda, T. & Takahashi, N., 2020 Jan 15, In: Biochemical and biophysical research communications. 521, 3, p. 769-774 6 p.

    Research output: Contribution to journal › Article › peer-review

    13 Citations (Scopus)

  • The effect of aldosterone on adiposity - The role of glucose absorption in the small intestine

    Shirai, H., Sato, E., Sekimoto, A., Uchida, T., Oe, Y., Ito, S., Sato, H. & Takahashi, N., 2020 Oct 22, In: Biochemical and biophysical research communications. 531, 4, p. 628-635 8 p.

    Research output: Contribution to journal › Article › peer-review

    2 Citations (Scopus)
  • 2019

    Glomerular injury is exacerbated in lupus-prone MRL/lpr mice treated with a protease-activated receptor 2 antagonist

    Itto, R., Oe, Y., Imaruoka, K., Sato, E., Sekimoto, A., Yamakage, S., Kumakura, S., Sato, H., Ito, S. & Takahashi, N., 2019, In: Tohoku Journal of Experimental Medicine. 249, 2, p. 127-133 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Citations (Scopus)

  • Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

    Kikuchi, K., Saigusa, D., Kanemitsu, Y., Matsumoto, Y., Thanai, P., Suzuki, N., Mise, K., Yamaguchi, H., Nakamura, T., Asaji, K., Mukawa, C., Tsukamoto, H., Sato, T., Oikawa, Y., Iwasaki, T., Oe, Y., Tsukimi, T., Fukuda, N. N., Ho, H. J., Nanto-Hara, F., & 36 othersOgura, J., Saito, R., Nagao, S., Ohsaki, Y., Shimada, S., Suzuki, T., Toyohara, T., Mishima, E., Shima, H., Akiyama, Y., Akiyama, Y., Ichijo, M., Matsuhashi, T., Matsuo, A., Ogata, Y., Yang, C. C., Suzuki, C., Breeggemann, M. C., Heymann, J., Shimizu, M., Ogawa, S., Takahashi, N., Suzuki, T., Owada, Y., Kure, S., Mano, N., Soga, T., Wada, T., Kopp, J. B., Fukuda, S., Hozawa, A., Yamamoto, M., Ito, S., Wada, J., Tomioka, Y. & Abe, T., 2019 Dec 1, In: Nature communications. 10, 1, 1835.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    113 Citations (Scopus)

  • Nicotinamide alleviates kidney injury and pregnancy outcomes in lupus-prone MRL/lpr mice treated with lipopolysaccharide

    Imaruoka, K., Oe, Y., Fushima, T., Sato, E., Sekimoto, A., Sato, H., Sugawara, J., Ito, S. & Takahashi, N., 2019 Mar 19, In: Biochemical and biophysical research communications. 510, 4, p. 587-593 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Citations (Scopus)

  • Protease-activated receptor 2 exacerbates cisplatin-induced nephrotoxicity

    Watanabe, M., Oe, Y., Sato, E., Sekimoto, A., Sato, H., Ito, S. & Takahashi, N., 2019 Apr, In: American Journal of Physiology - Renal Physiology. 316, 4, p. F654-F659

    Research output: Contribution to journal › Article › peer-review

    16 Citations (Scopus)

  • Protease-activated receptor 2 protects against VEGF inhibitor-induced glomerular endothelial and podocyte injury

    Oe, Y., Fushima, T., Sato, E., Sekimoto, A., Kisu, K., Sato, H., Sugawara, J., Ito, S. & Takahashi, N., 2019 Dec 1, In: Scientific reports. 9, 1, 2986.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Citations (Scopus)
  • 2018

    Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase

    Oe, Y., Ko, M., Fushima, T., Sato, E., Karumanchi, S. A., Sato, H., Sugawara, J., Ito, S. & Takahashi, N., 2018 Dec 1, In: Scientific reports. 8, 1, 102.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Citations (Scopus)

  • Impact of the oral adsorbent AST-120 on organ-specific accumulation of uremic toxins: LC-MS/MS and MS imaging techniques

    Sato, E., Saigusa, D., Mishima, E., Uchida, T., Miura, D., Morikawa-Ichinose, T., Kisu, K., Sekimoto, A., Saito, R., Oe, Y., Matsumoto, Y., Tomioka, Y., Mori, T., Takahashi, N., Sato, H., Abe, T., Niwa, T. & Ito, S., 2018 Jan, In: Toxins. 10, 1, 19.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Citations (Scopus)

  • Relationship between short term variability (STV) and onset of cerebral hemorrhage at ischemia-reperfusion load in fetal growth restricted (FGR) mice

    Minato, T., Ito, T., Kasahara, Y., Ooshio, S., Fushima, T., Sekimoto, A., Takahashi, N., Yaegashi, N. & Kimura, Y., 2018 May 18, In: Frontiers in Physiology. 9, MAY, 478.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Citations (Scopus)
  • 2017

    Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus

    Suzuki, T., Seki, S., Hiramoto, K., Naganuma, E., Kobayashi, E. H., Yamaoka, A., Baird, L., Takahashi, N., Sato, H. & Yamamoto, M., 2017 Feb 24, In: Nature communications. 8, 14577.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    51 Citations (Scopus)

  • Nicotinamide ameliorates a preeclampsia-like condition in mice with reduced uterine perfusion pressure

    Fushima, T., Sekimoto, A., Oe, Y., Sato, E., Ito, S., Sato, H. & Takahashi, N., 2017, In: American Journal of Physiology - Renal Physiology. 312, 2, p. F366-F372

    Research output: Contribution to journal › Article › peer-review

    14 Citations (Scopus)

  • Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes

    Nezu, M., Souma, T., Yu, L., Sekine, H., Takahashi, N., Zu-Sern Wei, A., Ito, S., Fukamizu, A., Zsengeller, Z. K., Nakamura, T., Hozawa, A., Ananth Karumanchi, S., Suzuki, N. & Yamamoto, M., 2017 May 16, In: Science Signaling. 10, 479, 5711.

    Research output: Contribution to journal › Article › peer-review

    54 Citations (Scopus)

  • Protease–activated receptor 2 exacerbates adenine–induced renal tubulointerstitial injury in mice

    Hayashi, S., Oe, Y., Fushima, T., Sato, E., Sato, H., Ito, S. & Takahashi, N., 2017 Jan 29, In: Biochemical and biophysical research communications. 483, 1, p. 547-552 6 p.

    Research output: Contribution to journal › Article › peer-review

    19 Citations (Scopus)
  • 2016

    Coagulation Factor Xa and Protease-Activated Receptor 2 as Novel Therapeutic Targets for Diabetic Nephropathy

    Oe, Y., Hayashi, S., Fushima, T., Sato, E., Kisu, K., Sato, H., Ito, S. & Takahashi, N., 2016 Aug 1, In: Arteriosclerosis, thrombosis, and vascular biology. 36, 8, p. 1525-1533 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    61 Citations (Scopus)

  • Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease

    Sato, E., Mori, T., Mishima, E., Suzuki, A., Sugawara, S., Kurasawa, N., Saigusa, D., Miura, D., Morikawa-Ichinose, T., Saito, R., Oba-Yabana, I., Oe, Y., Kisu, K., Naganuma, E., Koizumi, K., Mokudai, T., Niwano, Y., Kudo, T., Suzuki, C., Takahashi, N., & 4 othersSato, H., Abe, T., Niwa, T. & Ito, S., 2016 Nov 10, In: Scientific reports. 6, 36618.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    97 Citations (Scopus)

  • Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia

    Li, F., Fushima, T., Oyanagi, G., Townley-Tilson, H. W. D., Sato, E., Nakada, H., Oe, Y., Hagaman, J. R., Wilder, J., Li, M., Sekimoto, A., Saigusa, D., Sato, H., Ito, S., Jennette, J. C., Maeda, N., Karumanchi, S. A., Smithies, O. & Takahashi, N., 2016 Nov 22, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13450-13455 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Citations (Scopus)

  • Reduced uterine perfusion pressure (RUPP) model of preeclampsia in Mice

    Fushima, T., Sekimoto, A., Minato, T., Ito, T., Oe, Y., Kisu, K., Sato, E., Funamoto, K., Hayase, T., Kimura, Y., Ito, S., Sato, H. & Takahashi, N., 2016 May, In: PloS one. 11, 5, e0155426.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    58 Citations (Scopus)
  • 2015

    A novel and sensitive assay for heme oxygenase activity

    Iwamori, S., Sato, E., Saigusa, D., Yoshinari, K., Ito, S., Sato, H. & Takahashi, N., 2015 Sept 1, In: American Journal of Physiology - Renal Physiology. 309, 7, p. F667-F671

    Research output: Contribution to journal › Article › peer-review

    8 Citations (Scopus)
  • 2014

    A survey of self-medication practices and related factors in the general population: The ohasama study

    Satoh, M., Matsumoto, A., Hara, A., Iwamori, S., Obara, T., Kikuya, M., Metoki, H., Hosak, M., Asayama, K., Takahashi, N., Sato, H., Mano, N., Imai, Y. & Ohkubo, T., 2014, In: Yakugaku Zasshi. 134, 12, p. 1347-1355 9 p.

    Research output: Contribution to journal › Article › peer-review

    5 Citations (Scopus)

  • Combinations of olmesartan and a calciumchannel blocker or a diuretic inelderly hypertensive patients: A randomized, controlled trial

    Ogihara, T., Saruta, T., Rakugi, H., Saito, I., Shimamoto, K., Matsuoka, H., Shimada, K., Ito, S., Horiuchi, M., Imaizumi, T., Takishita, S., Higaki, J., Katayama, S., Kimura, G., Umemura, S., Ura, N., Hayashi, K., Odawara, M., Tanahashi, N., Ishimitsu, T., & 850 othersKashihara, N., Morita, S., Teramukai, S., Anno, T., Aoyama, S., Arima, N., Bando, Y., Dohi, Y., Fujioka, H., Fukuda, M., Fukuda, S., Fukuta, M., Futamura, Y., Hirakawa, Y., Imaeda, K., Imai, H., Imamura, A., Ito, M., Ito, O., Ito, T., Iwa, T., Izumi, J., Kaga, Y., Kanematsu, K., Kato, Y., Kawata, Y., Kitamura, T., Kobayashi, K., Koyasu, M., Kuwabara, S., Kuzuya, M., Maekawa, M., Mihara, H., Mitsuguchi, F., Murohara, T., Narita, T., Negi, K., Numaguchi, Y., Ohya, T., Okayama, N., Okuma, K., Ozaki, N., Ozeki, N., Sato, K., Sawada, T., Seino, Y., Suezawa, M., Suzuki, T., Suzuki, Y., Takahashi, N., Takahashi, R., Tanaka, N., Wakida, Y., Watanuki, H., Watarai, M., Yamada, K., Yamashita, S., Yoshikane, M., Goto, M., Ishida, Y., Kimura, H., Takahashi, K., Yashima, N., Abe, Y., Fujiwara, S., Higashino, H., Kaizuka, M., Minami, O., Ogiu, Y., Osanai, T., Sasaki, T., Sato, A., Sugimoto, K., Takahashi, H., Tanabe, K., Azuma, D., Ibuki, C., Inoya, H., Iyo, T., Kusaka, M., Ogawa, M., Okubo, Y., Rinno, H., Sano, M., Shishikura, T., Takahara, H., Takano, M., Takemura, T., Yamamoto, S., Yonemitsu, Y., Hasui, M., Honda, T., Igase, M., Kimoto, S., Kohno, K., Kondo, S., Oonishi, T., Saeki, H., Sunayama, T., Takahashi, H., Wakisaka, C., Watanabe, H., Watanabe, K., Iwahori, Y., Lau, A. H. C., Ando, S., Eguchi, H., Fujino, M., Fukui, J., Gondo, T., Hatakeyama, S., Hirano, K., Hirooka, Y., Ikeda, H., Inou, T., Jinnouchi, T., Kadokami, T., Kai, H., Kameo, H., Kaneyuki, M., Katoh, A., Kishikawa, H., Koiwaya, H., Kusaba, K., Maeda, S., Maki, S., Matsumoto, M., Matsumoto, T., Matsumura, J., Matsuo, S., Meno, H., Miki, S., Miyagi, J., Miyauchi, T., Mori, S., Nagashima, M., Nagata, S., Nakamura, R., Nakamura, T., Niiyama, H., Noda, K., Nohara, M., Ohta, Y., Onitsuka, I., Otonari, T., Ouma, S., Sakisaka, T., Saku, K., Sasaki, K., Sasaki, S., Sawayama, Y., Shihara, M., Shiota, K., Shirakawa, K., Tachikawa, Y., Takemura, S., Takeuchi, T., Tanabe, M., Tanaka, M., Tashiro, H., Tatsukawa, M., Tsuchihashi, T., Tsuiki, T., Tsutsui, T., Uehara, Y., Umei, H., Yamada, T., Yamagata, J., Ajihara, T., Hagiwara, K., Imamura, S., Inoue, M., Konno, I., Konta, K., Kubota, Y., Kumakawa, H., Kuwana, T., Mitsuhashi, H., Miyazaki, Y., Nagashima, J., Nambu, M., Nishimaki, T., Sato, M., Taneda, Y., Tezuka, T., Yabuki, T., Ando, F., Fuwa, Y., Umeda, S., Araki, O., Furushima, Y., Hattori, Y., Hirabayashi, H., Horigome, M., Hoshino, J., Iguchi, C., Inamura, H., Kawauchi, H., Kogure, S., Kubo, H., Naganuma, F., Nagao, T., Nagao, T., Nagata, T., Nakashima, H., Shimizu, Y., Shoda, H., Tachibana, M., Yabe, K., Kuwashima, R., Mouri, R., Murakami, T., Muraoka, H., Nomura, S., Okuno, F., Sasaki, N., Sasaki, R., Satoh, T., Shirataki, M., Sugino, H., Takahashi, H., Takemoto, H., Ashihara, J., Betsuyaku, T., Fujita, T., Haga, T., Hayashi, M., Hayashi, Y., Hirasawa, K., Ishii, Y., Ishimoto, R., Komakine, T., Kyuma, M., Maeda, I., Matsuda, H., Matsuki, T., Matsumoto, T., Mito, T., Mizutani, M., Morimoto, H., Natori, S., Nishimiya, T., Nishimura, M., Oimatsu, H., Ooiwa, H., Saitoh, S., Sasagawa, Y., Segawa, T., Shuke, H., Sotozono, K., Takagi, S., Tanaka, S., Tashi, M., Tsubokura, T., Ueno, Y., Urabe, K., Yamauchi, K., Yoshida, H., Amano, M., Hiroumi, Y., Iiyama, K., Kido, H., Kosaka, A., Nogami, A., Okada, M., Shigenobu, M., Shigeta, R., Takagi, S., Takamiya, T., Takemura, T., Tomimoto, S., Tsuboi, T., Abe, N., Akaogi, E., Iida, S., Ito, K., Jonouchi, H., Matsushima, T., Miura, H., Miyazaki, M., Okubo, S., Araki, T., Iritani, O., Masuya, K., Morimoto, S., Nakahashi, T., Wakasa, Y., Yanagi, M., Abe, Y., Ito, H., Kawakami, T., Kawamorita, Y., Okamoto, H., Omori, H., Suzuki, T., Yoshida, T., Akiyama, K., Fujita, S., Hamamoto, T., Hasegawa, K., Hattori, M., Imachi, H., Ishida, T., Ishihama, H., Kaifu, K., Kishikawa, H., Kono, M., Kunishige, M., Maeta, T., Masugata, H., Matsumoto, I., Matsuoka, N., Miki, H., Mori, S., Morita, T., Nishijima, Y., Ohashi, E., Okauchi, Y., Okura, T., Onishi, Y., Ono, K., Senda, S., Seo, I., Sugimoto, Y., Tada, M., Yokoi, K., Yoshinare, K., Arikawa, K., Hayashi, Y., Iida, K., Miyata, S., Mizoguchi, H., Osako, A., Saishoji, S., Shimozono, I., Takenouchi, S., Tanaka, S., Furuki, T., Hatori, N., Iwaki, T., Kametsu, E., Kawafune, T., Kobayashi, I., Kubo, T., Michishita, I., Nonaka, F., Numata, H., Ogata, A., Okubo, K., Sano, T., Sawada, R., Sekino, T., Shimizu, N., Shionoiri, H., Tsuchiya, H., Watanabe, Y., Yamamoto, H., Yasuda, G., Aoki, M., Iwasaki, Y., Kawamoto, H., Kitagawa, S., Matsumoto, M., Nishinaga, M., Nishiyama, M., Tsuboi, K., Ueda, I., Yabe, T., Yamada, H., Yoshida, T., Azuma, K., Doi, O., Fukami, R., Horio, Y., Ichikawa, Y., Ikeda, S., Inaba, T., Mimori, S., Ohmori, K., Sasaki, K., Sato, A., Toyama, H., Toyama, Y., Hamasaki, T., Hayashi, H., Isono, T., Kageyama, S., Komaki, K., Matoba, S., Matsubara, H., Matubara, T., Nakagawa, C., Nishi, D., Nishi, M., Oiwa, K., Takamatsu, H., Takashima, H., Takegami, T., Takenaka, K., Yamada, H., Yasuda, Y., Horiguchi, M., Iemura, J., Isaka, N., Ishiga, T., Kato, T., Kitamura, T., Kobayashi, M., Setsuda, M., Shimono, K., Abe, M., Abe, T., Abe, Y., Akino, Y., Ebina, H., Hirasawa, G., Hirasawa, K., Kamada, H., Kishi, M., Kohama, K., Kyogoku, S., Matsuo, K., Meguro, Y., Miyasato, S., Morita, K., Nakagawa, H., Otake, Y., Saito, H., Sasaki, A., Sasaki, I., Sato, S., Uchida, N., Utsumi, Y., Yamaguchi, S., Hosokawa, K., Ishiyama, Y., Kariya, S., Komidori, H., Kuwabara, M., Ohta, H., Sonoda, S., Takii, M., Wake, N., Yokota, N., Iijima, A., Shinozaki, T., Takeda, T., Ito, A., Kawano, H., Koide, Y., Matsuoka, H., Nakao, K., Yamaguchi, K., Yamanaka, A., Furiya, Y., Kimu, T., Kuga, Y., Nishida, Y., Saito, Y., Sugie, K., Takami, T., Yamasaki, M., Kaneko, Y., Kawabata, H., Nakayama, S., Abe, Y., Ando, H., Fujino, T., Gotoh, K., Kakuma, T., Katsuragi, I., Kuroda, A., Masaki, T., Ninomiya, K., Okita, K., Ono, H., Watanabe, T., Yoshiiwa, A., Abe, K., Deguchi, S., Ikeda, F., Kataoka, H., Komai, N., Koten, K., Kusano, K., Maeda, N., Makino, H., Matano, S., Ohe, T., Shikata, K., Gushiken, M., Hamada, R., Matsushima, K., Shimabukuro, T., Tohma, S., Akagi, T., Akai, F., Amatsu, T., Babaya, N., Ban, S., Fujii, K., Fujimoto, M., Fujimura, Y., Fukumoto, S., Funauchi, M., Hanada, H., Hasegawa, K., Hayashi, N., Hibuse, T., Higashida, M., Honde, H., Imagawa, A., Imamura, Y., Inoue, S., Ishii, R., Ishikawa, K., Ishitani, K., Ito, H., Kaito, S., Kamitani, A., Kamiya, K., Kasayuki, N., Kawanami, R., Kawasaki, T., Kijima, Y., Kinoshita, K., Kishibuchi, M., Kitamura, Y., Kobayashi, M., Kono, T., Maeda, Y., Masaki, K., Matsumoto, H., Matsuoka, S., Matsuwaka, R., Minamikata, K., Miyagawa, M., Miyamoto, H., Miyamoto, M., Miyazaki, E., Miyoshi, K., Mune, M., Nakagawa, N., Nakagawa, Y., Nakamura, F., Nakamura, T., Nakanishi, K., Nakatani, Y., Nariyama, J., Nishida, H., Nishino, M., Nishiyama, M., Nishizawa, K., Nohara, R., Nose, A., Ogasawara, H., Ogawa, R., Ohno, Y., Ojima, M., Okuyama, Y., Otani, H., Otani, S., Park, H., Saito, H., Sakai, A., Sakamoto, H., Sata, H., Sekine, Y., Shinozuka, T., Suga, T., Sugimoto, K., Sugiyama, M., Suyama, K., Suyama, K., Tachi, J., Takagi, T., Takaori, C., Takenaka, M., Tamai, T., Tanaka, K., Tanaka, Y., Tane, K., Taniura, M., Tatsuda, N., Teramoto, Y., Teranaka, K., Teranishi, S., Terasaki, J., Toki, K., Tsuji, K., Tsuji, Y., Tsunetoshi, T., Ujino, K., Umeki, S., Wakagi, N., Wakaki, N., Yamaguchi, K., Yamamoto, Y., Yanagitani, S., Yoshida, M., Yoshimoto, H., Yoshioka, H., Ikeda, H., Matsumoto, M., Nagae, K., Nishiyama, M., Noda, K., Ohga, M., Akui, M., Aoki, H., Arafune, J., Arai, M., Arai, T., Asami, I., Eguchi, K., Fujino, T., Fujinuma, H., Fukata, H., Fukuda, J., Hamasaki, T., Haneda, M., Hisauchi, I., Hogi, T., Ichikawa, M., Iijima, T., Inoue, H., Inoue, Y., Kakinuma, T., Kanai, H., Kaneko, U., Kano, T., Katsumi, T., Kawashima, T., Kogure, K., Komuro, O., Kubouchi, Y., Kujirai, N., Kurokawa, K., Lee, T., Maeda, K., Majima, T., Maruyama, Y., Mashiba, S., Mashiko, K., Matsumoto, K., Matsuzawa, M., Mitsugi, Y., Morita, J., Nakajima, C., Nakazato, Y., Nashida, Y., Nasuhara, H., Numajiri, Y., Ogasawara, T., Okudaira, T., Osawa, I., Otani, N., Otsuka, A., Ozawa, Y., Sakai, T., Sakai, Y., Shimizu, K., Shinozaki, T., Shirai, M., Shiroma, K., Shuto, H., Suzuki, H., Tada, A., Takagi, M., Takahashi, K., Takahashi, N., Taniguchi, A., Tonegawa, Y., Toyoda, M., Tsuchiya, T., Uchida, M., Uchino, H., Wada, H., Wada, O., Yoshioka, H., Horie, H., Ichikawa, M., Ikenoue, K., Kawashima, T., Mizuhara, H., Ono, S., Ishikawa, S., Kawakami, K., Yano, S., Kubota, N., Nakagawa, A., Shigemasa, T., Suwa, S., Akabane, T., Amagai, M., Asanobu, Y., Horinaka, S., Iijima, T., Kasai, K., Kataoka, T., Kobayashi, M., Masuda, T., Nakano, I., Namekawa, M., Numabe, A., Ono, A., Sakata, K., Taguchi, I., Tomotsune, T., Toyoda, S., Arizumi, M., Morimoto, Y., Ota, A., Sawada, S., Yata, K., Akita, H., Akitsu, T., Amemiya, K., Ando, M., Aoki, N., Aoyagi, J., Baba, T., Degawa, T., Eto, S., Fujimoto, K., Fukuda, H., Furukawa, T., Goto, I., Hachiya, A., Hanatani, Y., Hara, K., Haruta, T., Hasegawa, K., Hatano, T., Hayashi, M., Hirano, T., Hiratsuka, M., Horikawa, Y., Horiuchi, T., Hosoya, M., Ichikawa, K., Iguchi, K., Imai, H., Ishibashi, K., Ishida, K., Ishii, Y., Ishiwata, S., Iwama, T., Kadota, H., Kaku, S., Kamisaka, Y., Kanbara, R., Kanematsu, T., Kashiwagi, A., Kawa, I., Kawai, B., Kawai, M., Kiuchi, S., Kiyozuka, T., Koba, S., Kobayashi, H., Koike, K., Kojima, H., Koshibu, E., Koshibu, Y., Kubo, I., Kuga, K., Kushiro, T., Miyakata, S., Miyakawa, M., Miyoshi, F., Mochida, Y., Moriyama, N., Myojo, T., Nagashima, M., Nakada, H., Nakai, T., Nakamura, T., Nakaya, Y., Nishizawa, M., Nishizawa, S., Oba, K., Obu, Y., Ohara, N., Okazaki, M., Okazaki, Y., Okumura, K., Ono, T., Osamura, Y., Otsuka, M., Ouchi, M., Sakamoto, N., Sakata, Y., Saneshige, S., Sasajima, M., Satoi, T., Sengoku, Y., Shibuya, K., Shimizu, H., Shimokado, K., Shoji, M., Tabata, H., Takahashi, A., Takakura, H., Takao, T., Taya, M., Tomonari, H., Tsunematsu, T., Uehata, A., Umezawa, T., Usui, H., Watanabe, T., Yajima, Y., Yamada, F., Yamada, K., Yamaguchi, A., Yamaguchi, T., Yamamoto, K., Yamamoto, M., Hamada, T., Hisatome, I., Arita, K., Arita, M., Doi, E., Furuta, H., Hano, T., Hashizume, T., Hibino, A., Kodama, N., Saika, A., Ueda, J., Fujita, T., Ito, T., Sakano, M., Sugawara, T., Tachibana, H., Toda, H., Fujimoto, S., Furui, T., Hadano, Y., Kaneko, T., Kawabata, A., Kawamoto, S., Mezuki, M., Mochizuki, M., Nakatsuka, M., Ono, S., Tahara, N., Kuroda, M. & Manabe, H., 2014 Oct 1, In: Journal of hypertension. 32, 10, p. 2054-2063 10 p.

    Research output: Contribution to journal › Article › peer-review

    40 Citations (Scopus)
  • 2012

    Associations between day-by-day variability in blood pressure measured at home and antihypertensive drugs: The J-HOME-morning study home

    Ishikura, K., Obara, T., Kato, T., Kikuya, M., Shibamiya, T., Shinki, T., Ikeda, U., Kobayashi, Y., Metoki, H., Mano, N., Kuriyama, S., Ohkubo, T., Imai, Y., Yoshida, M., Aoki, S., Ido, H., Ito, K., Kikuchi, K., Maeda, I., Mito, T., & 299 othersNunokawa, A., Oda, K., Suzuki, N., Takagawa, Y., Tateda, K., Tateda, S., Akimot, M., Tashima, G., Fujii, Y., Onodera, G., Onodera, T., Sugiuchi, N., Suzuki, Y., Domon, R., Hayashi, T., Ishibashi, K., Ito, K., Kataoka, S., Kyogoku, S., Mashiko, H., Matsuo, K., Otake, Y., Saito, J., Shishido, Y., Takayama, A., Tanno, Y., Toyota, S., Uchida, N., Yambe, M., Fujioka, M., Kimura, Y., Matsuoka, H., Sasaki, K., Wada, M., Yamamoto, H., Goto, T., Kamimura, Y., Kitamura, H., Matsuura, Y., Nakayama, Y., Araki, F., Miyazaki, Y., Sakata, T., Sakuma, H., Sato, T., Shimizu, K., Yoshida, M., Deguchi, Y., Kano, T., Nishiyama, A., Shinotsuka, I., Kobayashi, T., Kumakura, S., Masuda, T., Watanabe, T., Honzawa, T., Kubo, H., Aoki, H., Kanozawa, S., Koide, H., Nishiyama, K., Sakamoto, K., Suda, J., Tagaya, T., Yamada, A., Yamanaka, K., Hasegawa, R., Hirai, S., Horibe, K., Jujo, A., Suzuki, M., Tamiya, N., Ueda, T., Umimura, T., Aoki, N., Arai, S., Himeno, T., Ikeda, T., Inoue, H., Itagaki, Y., Kamata, F., Kamegai, M., Kato, M., Kijima, S., Kotou, F., Kurokawa, T., Kurumatani, H., Minagawa, K., Miura, T., Miyoshi, Y., Morikawa, T., Morita, T., Nago, M., Nakada, H., Nakagawa, H., Nakamura, J., Niwa, A., Osuga, E., Ozaki, H., Sasaki, A., Sugahara, H., Suzuki, K., Tamura, H., Tomonari, H., Yamada, M., Kikuchi, H., Mikawa, T., Minamisawa, K., Miyakawa, M., Nishimura, M., Shinkai, T., Ushiyama, M., Yamamoto, H., Yokoyama, S., Horiuchi, A., Nagasaka, M., Fujita, M., Hoshiyama, N., Ikeda, M., Sakairi, A., Shinozaki, T., Takaki, H., Uchiba, K., Yanagisawa, H., Kobayashi, S., Sasaki, K., Takahashi, M., Takahashi, S., Doniwa, K., Higashi, H., Ohya, N., Yasuhara, M., Saiki, S., Ando, H., Fujii, M., Miyoshi, K., Fuchimoto, K., Kogure, M., Sugiura, K., Suzuki, T., Takahashi, N., Takahira, Y., Adachi, N., Koyama, Y., Miyazaki, Y., Nakamura, S., Narita, G., Nojiri, O., Okamoto, Y., Sakakura, K., Takasawa, M., Takenaka, T., Tatematsu, H., Uno, T., Watanabe, Y., Ishida, N., Kano, U., Morita, N., Okano, H., Takahashi, T., Yamaoka, O., Hayashi, H., Kuroda, O., Matsushita, Y., Mizuno, T., Taniguchi, Y., Yamashita, M., Arai, S., Fujimura, Y., Fujita, S., Hakuto, T., Ikuno, Y., Ishida, H., Kondo, R., Masaki, K., Nao, K., Numata, A., Saeki, S., Sakamoto, H., Suyama, K., Takada, K., Takenaka, T., Teramoto, K., Ueda, G., Wakaki, N., Yokotani, T., Handa, N., Katsuya, S., Kondo, K., Nagamatsu, K., Nakamura, K., Okano, T., Omori, H., Takahashi, N., Tsuji, Y., Yanaka, Y., Yonezawa, Y., Matsumura, Y., Nakamura, Y., Sawada, K., Shimomura, H., Suzuki, H., Furuta, K., Tamaki, N., Wanaka, Y., Inoue, A., Kamura, M., Yuhara, N., Fushimi, A., Ido, Y., Karai, I., Kurosumi, K., Maeda, N., Nishigaki, T., Nishihara, Y., Shindo, T., Yoshimoto, T., Furue, T., Ikeda, S., Kishizuchi, K., Ozawa, A., Ozawa, J., Sasaki, N., Sasaki, S., Shigeto, N., Tanabe, M., Yoshimoto, H., Hirokuni, T., Nakatsuka, M., Noda, T., Tosaka, M., Toshima, Y., Wada, T., Wakimoto, M., Yamanaka, T., Kimura, M., Ota, A., Fukui, T., Furumoto, W., Mashima, K., Nakatsu, T., Yokoi, T., Nakayama, T., Azakami, S., Eto, T., Fujishima, Y., Fukudome, Y., Goto, S., Hara, H., Harada, Y., Hoashi, T., Imoto, K., Inoue, R., Ishizaki, T., Ito, Y., Ito, T., Jinnochi, T., Kawasaki, A., Miake, S., Miyagi, J., Nagasawa, K., Okada, K., Okita, T., Otonari, T., Tachikawa, Y., Takaki, K., Tanaka, S., Urata, H., Yoshioka, S., Ikeda, H., Kaihara, R., Kuwahara, T., Matsuo, I., Nagata, O., Saito, H., Shindo, R., Takeoka, Y., Ito, A., Kusano, S., Tokunaga, M., Hamasaki, S., Honda, Y., Iwai, K., Izuno, K., Koyama, K., Maeda, H., Maki, A., Semba, F., Yi, S., K, H., Ninomiya, K., Endo, Y., Ezaki, Y., Narita, R., Hatashida, I., Komaki, S., Kuroiwa, R., Yoshii, H. & Nakamura, Y., 2012 Jul 1, In: Clinical and Experimental Hypertension. 34, 4, p. 297-304 8 p.

    Research output: Contribution to journal › Article › peer-review

    24 Citations (Scopus)

  • Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

    Bordicchia, M., Liu, D., Amri, E. Z., Ailhaud, G., Dessì-Fulgheri, P., Zhang, C., Takahashi, N., Sarzani, R. & Collins, S., 2012 Mar 1, In: Journal of Clinical Investigation. 122, 3, p. 1022-1036 15 p.

    Research output: Contribution to journal › Article › peer-review

    663 Citations (Scopus)

  • Decreased eNOS and high fat diet in diabetic nephropathy

    Takahashi, N., Li, F., Wang, C. H., Mackman, N., Maeda, N., Smithies, O. & Jennette, J. C., 2012, In: Therapeutic Research. 33, 8, p. 1206-1208 3 p.

    Research output: Contribution to journal › Article › peer-review

  • eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype

    Li, F., Hagaman, J. R., Kim, H. S., Maeda, N., Jennette, J. C., Faber, J. E., Karumanchi, S. A., Smithies, O. & Takahashi, N., 2012 Apr, In: Journal of the American Society of Nephrology. 23, 4, p. 652-660 9 p.

    Research output: Contribution to journal › Article › peer-review

    77 Citations (Scopus)
  • 2011

    A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy

    Wang, C. H., Li, F., Hiller, S., Kim, H. S., Maeda, N., Smithies, O. & Takahashi, N., 2011 Feb 1, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 5, p. 2070-2075 6 p.

    Research output: Contribution to journal › Article › peer-review

    49 Citations (Scopus)
  • 2010

    Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet

    Li, F., Wang, C. H., Wang, J. G., Thai, T., Boysen, G., Xu, L., Turner, A. L., Wolberg, A. S., Mackman, N., Maeda, N. & Takahashi, N., 2010 Oct, In: Journal of Thrombosis and Haemostasis. 8, 10, p. 2122-2132 11 p.

    Research output: Contribution to journal › Article › peer-review

    25 Citations (Scopus)

  • Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice

    Wende, A. R., Soto, J., Olsen, C. D., Pires, K. M. P., Schell, J. C., Larrieu-Lahargue, F., Litwin, S. E., Kakoki, M., Takahashi, N., Smithies, O. & Abel, E. D., 2010 Aug, In: Endocrinology. 151, 8, p. 3536-3542 7 p.

    Research output: Contribution to journal › Article › peer-review

    16 Citations (Scopus)
  • 2007

    Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel

    Yamaguchi, N., Takahashi, N., Xu, L., Smithies, O. & Meissner, G., 2007 May 1, In: Journal of Clinical Investigation. 117, 5, p. 1344-1353 10 p.

    Research output: Contribution to journal › Article › peer-review

    103 Citations (Scopus)

  • Increased Energy Expenditure, Dietary Fat Wasting, and Resistance to Diet-Induced Obesity in Mice Lacking Renin

    Takahashi, N., Li, F., Hua, K., Deng, J., Wang, C. H., Bowers, R. R., Bartness, T. J., Kim, H. S. & Harp, J. B., 2007 Dec 5, In: Cell Metabolism. 6, 6, p. 506-512 7 p.

    Research output: Contribution to journal › Article › peer-review

    70 Citations (Scopus)

  • Progress report on the Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) study: Status at February 2004

    Hosohata, K., Saito, S., Asayama, K., Ohkubo, T., Kikuya, M., Metoki, H., Obara, T., Kato, T., Hashimoto, J., Totsune, K., Miura, Y., Imai, Y., Arakawa, K., Fujishima, M., Fujii, J., Fukiyama, K., Hisamichi, S., Iimura, O., Ishii, M., Omae, T., & 525 othersSaruta, T., Yoshinaga, K., Abe, I., Abe, K., Abukawa, T., Ashida, T., Dohba, N., Etoh, T., Fujimura, A., Fujita, T., Fukui, A., Gotoh, T., Hama, H., Hano, T., Hayashi, H., Hayashida, N., Hayashi, M., Hiramori, K., Hirai, Y., Hirata, Y., Hiwada, K., Hora, K., Ichikawa, S., Iida, T., Ikeda, T., Imaizumi, T., Ishikawa, K., Ito, I., Ito, M., Ito, S., Iwaoka, D., Kanamasa, K., Katagiri, T., Katayama, S., Kawamura, H., Kawano, Y., Kida, H., Kikuchi, K., Kimura, G., Kimura, K., Kitaoka, H., Kobayashi, S., Kohara, K., Kojima, S., Komuro, I., Kumagai, H., Kumagai, Y., Kusano, E., Kushiro, T., Kuwajima, I., Maruyama, Y., Masani, F., Matsubara, H., Matsubara, T., Matsumoto, M., Matsuoka, H., Matsuura, H., Mishima, Y., Miura, M., Miyamori, I., Mori, H., Murakami, H., Muratani, H., Nakagawa, M., Nakao, K., Naruse, M., Nishio, I., Ogihara, T., Ohta, M., Ohtsuka, K., Ohtsuka, Y., Ohuchi, Y., Oikawa, S., Okabe, M., Okumura, K., Saitoh, I., Saitoh, H., Sakata, T., Saku, K., Sasaki, H., Seino, M., Senda, S., Shimada, K., Shimamoto, K., Shimizu, M., Shiomi, T., Shirato, K., Sone, M., Suzuki, H., Suzuki, S., Takahashi, H., Takada, M., Takeda, K., Takeda, N., Takeshita, A., Takishita, S., Tanaka, S., Toba, K., Tochikubo, O., Tomoike, H., Ueno, Y., Umemura, S., Urata, H., Watanabe, T., Yamada, K., Yamaguchi, T., Yamakado, M., Yamamoto, Y., Yamamoto, Y., Yamashina, A., Yokoyama, H., Yoshimura, M., Satoh, H., Oka, Y., Katagiri, H., Kondo, Y., Shishido, H., Kohinata, A., Kanno, Y., Ikeda, H., Takahira, Y., Takahashi, T., Kimura, A., Funahashi, J., Takada, N., Hanazawa, T., Suzuki, N., Osugi, M., Hashimoto, J., Ogawa, Y., Miyamura, T., Masuda, Y., Tanaka, S., Tanaka, S., Koizumi, M., Ando, T., Endo, T., Tsuchida, A., Nanba, M., 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Watanabe, S., Hiwatashi, N., Yagi, C., Unakami, H., Asayama, K., Mouri, T., Watanabe, T., Kikuchi, K., Maruyama, N., Sone, M., Iwamoto, M., Naganuma, S., Mashiko, H., Ishii, H., Takaya, Y., Kamimoto, M., Shirai, A., Watanabe, R., Tohyama, Y., Araki, F., Sakuma, H., Amada, Y., Sato, E., Techigawara, M., Nakamura, K., Nakayama, T., Hasegawa, K., Hasegawa, K., Nagao, T., Minami, J., Kumagai, Y., Cho, T., Okamoto, K., Iguchi, T., Honzawa, T., Koitabashi, T., Yamada, T., Horikoshi, H., Nagao, T., Yoshimatsu, H., Seki, K., Akiyama, N., Suga, H., Matsunaga, R., Sinozaki, T., Ishimaru, Y., Yagi, N., Takikawa, H., Hukutome, T., Nakajima, C., Sato, H., Simizu, J., Arai, M., Koide, H., Takada, H., Sato, T., Umezu, T., Aoki, H., Nakamoto, H., Komahashi, K., Sekiya, S., Sugimoto, H., Arai, T., Suzuki, H., Inokuma, S., Funazaki, T., Yasuda, F., Kanouzawa, S., Yokota, C., Noguchi, Y., Hatano, M., Izumida, T., Hara, T., Muranaka, H., Suzuki, M., Ogawa, Y., Yabumoto, E., Matsushita, S., Kohzu, K., Sasaki, F., Hata, N., Yanagisawa, M., Ueda, T., Kurosawa, M., Doutare, S., Higashi, S., Kato, M., Hoshino, T., Fukuda, K., Ohtsuki, K., Ikeda, T., Kasatani, T., Yamada, T., Yatagai, S., Ohsuga, E., Yamakado, M., Kawamura, H., Mitsubayashi, H., Yamashina, S., Yamazaki, J., Nanjo, S., Ito, S., Teramoto, T., Gomi, T., Kato, S., Koekawa, N., Kuwaki, K., Ikeda, T., Hori, K., Arai, S., Koyama, H., Ichikawa, M., Hashimoto, A., Mori, H., Abe, S., Ohba, Y., Kurata, F., Miyakawa, M., Kimura, K., Hatori, Y., Ushiyama, M., Yamamoto, H., Adachi, M., Takayama, K., Shimizu, M., Iida, T., Asato, S., Uchiba, K., Watanabe, N., Kotani, M., Akaoka, F., Takahashi, S., Hirahara, K., Suzuki, S., Yamaguchi, Y., Ishikawa, S., Sasaki, K., Terada, Y., Ohhashi, S., Sakamaki, A., Hifumi, N., Ohno, T., Saeki, T., Suzaki, Y., Yamamoto, H., Nakagawa, T., Tomoda, F., Nishino, H., Ise, T., Takakuwa, H., Yokoyama, H., Kitakawa, S., Takasawa, K., Ohkura, T., Yamamoto, Y., Satake, K., Arai, Y., Nakayama, H., Sugiyama, S., Sugiura, K., Yokoyama, M., Ito, A., Okazaki, K., Saito, R., Mihara, J., Naito, A., Takahira, Y., Mori, T., Watanabe, M., Asai, S., Nojiri, O., Sakakura, K., Kozuka, M., Oyama, Y., Kawamura, Y., Inoko, T., Takeuchi, N., Tatematsu, H., Hayakawa, Y., Adachi, N., Tamagaki, N., Nakamura, T., Fukui, A., Amenomori, M., Kanaya, T., Masui, A., Hayashi, K., Nishi, S., Amari, M., Yoshida, K., Matsushita, Y., Sawada, S., Fujiwara, M., Ono, S., Tamai, K., Takemoto, Y., Kanemasa, T., Takenaka, T., Kitayama, K., Yasui, K., Fujita, S., Terayama, Y., Kato, N., Nagai, M., Takashima, H., Watanabe, K., Hirobe, N., Miyamoto, M., Sakamoto, N., Kurimoto, Y., Suzuki, N., Katsuya, S., Katsuya, T., Nagao, K., Nakamuta, K., Goto, S., Ueda, T., Imai, N., Sano, I., Ueda, H., Takahashi, N., Sada, T., Iwane, M., Suzuki, H., Yoshikawa, H., Tominaga, Y., Kamura, M., Ohtahara, A., Nakamura, Y., Osakada, M., Gen, M., Kahara, M., Yoshimoto, T., Mizuno, K., Furukawa, Y., Tokunaga, A., Sasaki, N., Matsumura, M., Furue, T., Iwasaki, K., Ichiki, K., Mizofuchi, S., Yokoi, T., Furumoto, W., Fukui, T., Fujino, K., Ohta, A., Ueda, S., Kitami, Y., Ohkura, T., Takeuchi, M., Yoshida, K., Nishiyama, S., Kawamoto, R., Kobaru, A., Endo, T., Kitano, K., Hirooka, Y., Tohaya, M., Miyazaki, Y., Onoyama, K., Miyagi, J., Kin, U., Fujishima, Y., Kuwahara, A., Shindo, R., Satake, Y., Moritsuka, T., Kuwahara, T., Hano, O., Takagi, Y., Suzuki, S., Abe, K., Sato, T., Kohno, M., Fujino, T., Wakayama, K., Aso, T., Goto, T., Ozaki, H., Ninomiya, K., Inobe, Y., Hamasaki, S., Inoue, J., Naomi, S., Iwaoka, T., Ono, T., Muta, Y., Endo, Y., Ohmori, H., Nagata, M., Wake, N., Kozawa, H., Tomino, Y., Ikeda, T., Yoshii, H., Nakamura, H., Fujimoto, N., Asato, T., Tozawa, M., Sunagawa, R., Nakamura, Y., Tomori, H. & Takashiba, K., 2007, In: Clinical and Experimental Hypertension. 29, 1, p. 69-81 13 p.

    Research output: Contribution to journal › Article › peer-review

    10 Citations (Scopus)

  • Tandem mass spectrometry measurements of creatinine in mouse plasma and urine for determining glomerular filtration rate

    Takahashi, N., Boysen, G., Li, F., Li, Y. & Swenberg, J. A., 2007 Feb, In: Kidney international. 71, 3, p. 266-271 6 p.

    Research output: Contribution to journal › Article › peer-review

    113 Citations (Scopus)
  • 2006

    Kidney function in mice lacking aldosterone

    Makhanova, N., Lee, G., Takahashi, N., Lopez, M. L. S., Gomez, R. A., Kim, H. S. & Smithies, O., 2006 Jan, In: American Journal of Physiology - Renal Physiology. 290, 1, p. F61-F69

    Research output: Contribution to journal › Article › peer-review

    44 Citations (Scopus)

  • Protein inhibitor of activated STAT3 inhibits adipogenic gene expression

    Deng, J., Hua, K., Caveney, E. J., Takahashi, N. & Harp, J. B., 2006 Jan 20, In: Biochemical and biophysical research communications. 339, 3, p. 923-931 9 p.

    Research output: Contribution to journal › Article › peer-review

    29 Citations (Scopus)

  • Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors

    Kakoki, M., Kizer, C. M., Yi, X., Takahashi, N., Kim, H. S., Bagnell, C. R., Edgell, C. J. S., Maeda, N., Jennette, J. C. & Smithies, O., 2006 May 1, In: Journal of Clinical Investigation. 116, 5, p. 1302-1309 8 p.

    Research output: Contribution to journal › Article › peer-review

    80 Citations (Scopus)
  • 2005

    Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene

    Nishikimi, T., Hagaman, J. R., Takahashi, N., Kim, H. S., Matsuoka, H., Smithies, O. & Maeda, N., 2005 Apr 1, In: Cardiovascular Research. 66, 1, p. 94-103 10 p.

    Research output: Contribution to journal › Article › peer-review

    24 Citations (Scopus)

  • Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type

    Takahashi, N., Lopez, M. L. S. S., Cowhig, J. E., Taylor, M. A., Hatada, T., Riggs, E., Lee, G., Gomez, R. A., Kim, H. S. & Smithies, O., 2005, In: Journal of the American Society of Nephrology. 16, 1, p. 125-132 8 p.

    Research output: Contribution to journal › Article › peer-review

    78 Citations (Scopus)
  • 2004

    Altering the expression in mice of genes by modifying their 3′ regions

    Kakoki, M., Tsai, Y. S., Kim, H. S., Hatada, S., Ciavatta, D. J., Takahashi, N., Arnold, L. W., Maeda, N. & Smithies, O., 2004 Apr, In: Developmental cell. 6, 4, p. 597-606 10 p.

    Research output: Contribution to journal › Article › peer-review

    41 Citations (Scopus)