A case of advanced gastric cancer treated with neoadjuvant chemotherapy of low-dose CPT-11 + CDDP

H. Tadatomo, K. Suzuki, M. Ando, S. Yamashita, K. Tanaka, S. Maruyama, Y. Harada, S. Ohnuma, N. Sakaniwa, Y. Koyanagi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Side effects due to administration of anti-cancer drugs often cause the treatment to be abandoned or a decrease in the amount of anti-cancer drugs. Recently, the anti-tumor effects of "low-dose CPT-11", which can be administered at the outpatient clinic, are reported. We performed "low-dose CPT-11 + CDDP" as a neoadjuvant chemotherapy to a patient with advanced gastric cancer. CPT-11 and CDDP combination chemotherapy caused very few side effects, so we could continue the treatment and achieve anti-tumor effects. Consequently, surgery could be performed, but disseminated metastasis was found so that the surgery ended as a non-curative operation. However, it was considered that this method of "low-dose CPT-11 + CDDP" was very effective as the neoadjuvant chemotherapy in a patient with advanced gastric cancer.

Original languageEnglish
Pages (from-to)821-824
Number of pages4
JournalJapanese Journal of Cancer and Chemotherapy
Volume28
Issue number6
Publication statusPublished - 2001 Jun

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