A case of Crohn's disease complicated with colonic cancer

Munenori Nagao, Yuji Funayama, Kouhei Fukushima, Chikashi Shibata, Kenichi Takahashi, Hitoshi Ogawa, Akihiko Hashimoto, Yoshitaka Kinouchi, Takayuki Masuda, Iwao Sasaki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


A 29-year-old man diagnosed with Crohn's disease at age 27 underwent emergency ileostomy for an intestinal obstruction on April 5, 2001. After his general condition improved, subtotal colectomy was done on November 8, 2001, due to stenosis of the descending colon. Histological examination of the descending colon showed transmural inflammation and granulomatous change, typical of Crohn's disease. The infiltration of well-differentiated adenocarcinoma in the diseased descending colon to the subserosal layer was also observed. p53 positive mucosa without structural atypia was found around the carcinoma. Follow-up has yet to indicate recurrence.

Original languageEnglish
Pages (from-to)1497-1502
Number of pages6
JournalJapanese Journal of Gastroenterological Surgery
Issue number8
Publication statusPublished - 2004


  • Colonic cancer
  • Crohn's disease


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