A 29-year-old man diagnosed with Crohn's disease at age 27 underwent emergency ileostomy for an intestinal obstruction on April 5, 2001. After his general condition improved, subtotal colectomy was done on November 8, 2001, due to stenosis of the descending colon. Histological examination of the descending colon showed transmural inflammation and granulomatous change, typical of Crohn's disease. The infiltration of well-differentiated adenocarcinoma in the diseased descending colon to the subserosal layer was also observed. p53 positive mucosa without structural atypia was found around the carcinoma. Follow-up has yet to indicate recurrence.
- Colonic cancer
- Crohn's disease