TY - JOUR
T1 - A case of curatively resected AFP producing gastric cancer that responded remarkably to 1 course of TS-1 and showed complete loss of multiple liver metastatic tumors
AU - Hatta, Waku
AU - Kumagai, Shinji
AU - Imamura, Junji
AU - Oikawa, Tomoyuki
AU - Asano, Yasunari
AU - Fujita, Hiroshi
AU - Aizawa, Hiroki
AU - Kaneko, Kenzo
AU - Kayaba, Shouichi
AU - Sawada, Masashi
AU - Kusuda, Kazuyuki
AU - Suzuki, Y.
AU - Takehana, Kou
AU - Endo, Yoshihiro
AU - Kitamura, Michihiko
AU - Kimizuka, Goro
PY - 2005/6
Y1 - 2005/6
N2 - A 73-year-old woman was admitted to our hospital for evaluation of hypochondralgia, and a thorough examination revealed an AFP producing gastric cancer with multiple liver metastases. One course of TS-1 100 mg/day for 4 weeks and discontinuation for 2 weeks was started from February, 2003. After 3 months, the level of AFP reduced remarkably from 53,700 ng/ml to the normal limit. The metastatic tumors in the liver showed regression, and after 14 months, CT scanning showed that the tumors had disappeared. Since the size of the original tumor showed no change, distal gastrectomy was performed, and curability A was achieved. We consider this rare case has significant value in terms of treatment of AFP producing gastric cancer with multiple liver metastases. We think the combination of surgery and chemotherapy such as TS-1 will lead to a better prognosis in such cases.
AB - A 73-year-old woman was admitted to our hospital for evaluation of hypochondralgia, and a thorough examination revealed an AFP producing gastric cancer with multiple liver metastases. One course of TS-1 100 mg/day for 4 weeks and discontinuation for 2 weeks was started from February, 2003. After 3 months, the level of AFP reduced remarkably from 53,700 ng/ml to the normal limit. The metastatic tumors in the liver showed regression, and after 14 months, CT scanning showed that the tumors had disappeared. Since the size of the original tumor showed no change, distal gastrectomy was performed, and curability A was achieved. We consider this rare case has significant value in terms of treatment of AFP producing gastric cancer with multiple liver metastases. We think the combination of surgery and chemotherapy such as TS-1 will lead to a better prognosis in such cases.
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M3 - Article
C2 - 15984531
AN - SCOPUS:21244492398
SN - 0385-0684
VL - 32
SP - 855
EP - 858
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 6
ER -