A Case of Laparoscopically Resected Giant Rectal Cancer Following Neoadjuvant Chemoradiotherapy

Takashi Aizawa, Hideaki Karasawa, Shinobu Ohnuma, Hideyuki Suzuki, Hirofumi Imoto, Akihiro Yamamura, Atsushi Kohyama, Takeshi Aoki, Kazuhiro Watanabe, Naoki Tanaka, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naito, Michiaki Unno

Research output: Contribution to journalArticlepeer-review


A woman in her 40s who presented to a local hospital with bloody stool was referred to our hospital. Colonoscopy showed a rectal tumor, and histological examination showed moderately differentiated adenocarcinoma. CT and MRI revealed that the tumor was 65mm in diameter with no distant metastasis. After the construction of ileostomy, neoadjuvant chemoradiothera- py(NACRT: 45 Gy/25 Fr, S-1 80mg/m2)was performed. The tumor shrank remarkably, and then we performed laparoscopy- assisted low anterior resection. Pathological examination revealed complete disappearance of the cancer cells in the primary site and no appearance of cancer cells in all dissected lymph nodes. NACRT has been recently reported to provide pathological complete response, and these patients are supposed to have a good prognosis. In our case, NACRT enhanced the performance of laparoscopic curative resection while preserving anal function. NACRT should contribute to the curative resection while preserving anal function in patients with locally advanced rectal cancer.

Original languageEnglish
Pages (from-to)1931-1933
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number13
Publication statusPublished - 2018 Dec 1

ASJC Scopus subject areas

  • Medicine(all)


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