A Case of Laparoscopically Resected Giant Rectal Cancer Following Neoadjuvant Chemoradiotherapy

Takashi Aizawa; Hideaki Karasawa; Shinobu Ohnuma; Hideyuki Suzuki; Hirofumi Imoto; Akihiro Yamamura; Atsushi Kohyama; Takeshi Aoki; Kazuhiro Watanabe; Naoki Tanaka; Hiroaki Musha; Fuyuhiko Motoi; Takashi Kamei; Takeshi Naito; Michiaki Unno

A Case of Laparoscopically Resected Giant Rectal Cancer Following Neoadjuvant Chemoradiotherapy

Takashi Aizawa, Hideaki Karasawa, Shinobu Ohnuma, Hideyuki Suzuki, Hirofumi Imoto, Akihiro Yamamura, Atsushi Kohyama, Takeshi Aoki, Kazuhiro Watanabe, Naoki Tanaka, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naito, Michiaki Unno

Research output: Contribution to journal › Article › peer-review

Abstract

A woman in her 40s who presented to a local hospital with bloody stool was referred to our hospital. Colonoscopy showed a rectal tumor, and histological examination showed moderately differentiated adenocarcinoma. CT and MRI revealed that the tumor was 65mm in diameter with no distant metastasis. After the construction of ileostomy, neoadjuvant chemoradiothera- py(NACRT: 45 Gy/25 Fr, S-1 80mg/m2)was performed. The tumor shrank remarkably, and then we performed laparoscopy- assisted low anterior resection. Pathological examination revealed complete disappearance of the cancer cells in the primary site and no appearance of cancer cells in all dissected lymph nodes. NACRT has been recently reported to provide pathological complete response, and these patients are supposed to have a good prognosis. In our case, NACRT enhanced the performance of laparoscopic curative resection while preserving anal function. NACRT should contribute to the curative resection while preserving anal function in patients with locally advanced rectal cancer.

Original language	English
Pages (from-to)	1931-1933
Number of pages	3
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	45
Issue number	13
Publication status	Published - 2018 Dec 1

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Medicine(all)

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title = "A Case of Laparoscopically Resected Giant Rectal Cancer Following Neoadjuvant Chemoradiotherapy",

abstract = "A woman in her 40s who presented to a local hospital with bloody stool was referred to our hospital. Colonoscopy showed a rectal tumor, and histological examination showed moderately differentiated adenocarcinoma. CT and MRI revealed that the tumor was 65mm in diameter with no distant metastasis. After the construction of ileostomy, neoadjuvant chemoradiothera- py(NACRT: 45 Gy/25 Fr, S-1 80mg/m2)was performed. The tumor shrank remarkably, and then we performed laparoscopy- assisted low anterior resection. Pathological examination revealed complete disappearance of the cancer cells in the primary site and no appearance of cancer cells in all dissected lymph nodes. NACRT has been recently reported to provide pathological complete response, and these patients are supposed to have a good prognosis. In our case, NACRT enhanced the performance of laparoscopic curative resection while preserving anal function. NACRT should contribute to the curative resection while preserving anal function in patients with locally advanced rectal cancer.",

author = "Takashi Aizawa and Hideaki Karasawa and Shinobu Ohnuma and Hideyuki Suzuki and Hirofumi Imoto and Akihiro Yamamura and Atsushi Kohyama and Takeshi Aoki and Kazuhiro Watanabe and Naoki Tanaka and Hiroaki Musha and Fuyuhiko Motoi and Takashi Kamei and Takeshi Naito and Michiaki Unno",

year = "2018",

month = dec,

day = "1",

language = "English",

volume = "45",

pages = "1931--1933",

journal = "Japanese Journal of Cancer and Chemotherapy",

issn = "0385-0684",

publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

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TY - JOUR

T1 - A Case of Laparoscopically Resected Giant Rectal Cancer Following Neoadjuvant Chemoradiotherapy

AU - Aizawa, Takashi

AU - Karasawa, Hideaki

AU - Ohnuma, Shinobu

AU - Suzuki, Hideyuki

AU - Imoto, Hirofumi

AU - Yamamura, Akihiro

AU - Kohyama, Atsushi

AU - Aoki, Takeshi

AU - Watanabe, Kazuhiro

AU - Tanaka, Naoki

AU - Musha, Hiroaki

AU - Motoi, Fuyuhiko

AU - Kamei, Takashi

AU - Naito, Takeshi

AU - Unno, Michiaki

PY - 2018/12/1

Y1 - 2018/12/1

N2 - A woman in her 40s who presented to a local hospital with bloody stool was referred to our hospital. Colonoscopy showed a rectal tumor, and histological examination showed moderately differentiated adenocarcinoma. CT and MRI revealed that the tumor was 65mm in diameter with no distant metastasis. After the construction of ileostomy, neoadjuvant chemoradiothera- py(NACRT: 45 Gy/25 Fr, S-1 80mg/m2)was performed. The tumor shrank remarkably, and then we performed laparoscopy- assisted low anterior resection. Pathological examination revealed complete disappearance of the cancer cells in the primary site and no appearance of cancer cells in all dissected lymph nodes. NACRT has been recently reported to provide pathological complete response, and these patients are supposed to have a good prognosis. In our case, NACRT enhanced the performance of laparoscopic curative resection while preserving anal function. NACRT should contribute to the curative resection while preserving anal function in patients with locally advanced rectal cancer.

AB - A woman in her 40s who presented to a local hospital with bloody stool was referred to our hospital. Colonoscopy showed a rectal tumor, and histological examination showed moderately differentiated adenocarcinoma. CT and MRI revealed that the tumor was 65mm in diameter with no distant metastasis. After the construction of ileostomy, neoadjuvant chemoradiothera- py(NACRT: 45 Gy/25 Fr, S-1 80mg/m2)was performed. The tumor shrank remarkably, and then we performed laparoscopy- assisted low anterior resection. Pathological examination revealed complete disappearance of the cancer cells in the primary site and no appearance of cancer cells in all dissected lymph nodes. NACRT has been recently reported to provide pathological complete response, and these patients are supposed to have a good prognosis. In our case, NACRT enhanced the performance of laparoscopic curative resection while preserving anal function. NACRT should contribute to the curative resection while preserving anal function in patients with locally advanced rectal cancer.

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M3 - Article

C2 - 30692401

AN - SCOPUS:85060653142

SN - 0385-0684

VL - 45

SP - 1931

EP - 1933

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

IS - 13

ER -

A Case of Laparoscopically Resected Giant Rectal Cancer Following Neoadjuvant Chemoradiotherapy

Abstract

ASJC Scopus subject areas

UN SDGs

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