A case of progressive focal nodular hyperplasia developed in a young patient taking oral contraceptives

Yuki Miyazaki, Yasuyuki Hara, Shigehito Miyagi, Chikashi Nakanishi, Kazuaki Tokodai, Wataru Nakanishi, Ryuichi Nishimura, Fumiyoshi Fujishima, Michiaki Unno, Takashi Kamei

Research output: Contribution to journalArticlepeer-review


The patient was a 25-year-old woman. In January 2015, a 23-mm single nodule was found in segment 7 of the liver by ultrasonography. The size of the nodule increased to 52 mm in March 2017, and the patient underwent percutaneous liver biopsy. Focal nodular hyperplasia (FNH) was suspected from the biopsy, but hepatic adenoma (HA) was not ruled out. The nodule size continued to increase after the biopsy, and the patient was transferred to our hospital for consultation. FNH was suspected from the radiological study. However, HA was not excluded as a possibility because the patient had taken an oral contraceptive and the nodule continued to increase in size. An extended right posterior sectionectomy was performed to address the concerns of malignant transformation and bleeding. The final diagnosis from the histological analysis was FNH. Progressive FNH in a young woman taking oral contraceptives is very rare and has not been reported before.

Original languageEnglish
Pages (from-to)127-134
Number of pages8
JournalActa Hepatologica Japonica
Issue number4
Publication statusPublished - 2019


  • Focal nodular hyperplasia
  • Hepatic adenoma
  • Oral contraceptive
  • Progressive FNH
  • Young patient

ASJC Scopus subject areas

  • Hepatology


Dive into the research topics of 'A case of progressive focal nodular hyperplasia developed in a young patient taking oral contraceptives'. Together they form a unique fingerprint.

Cite this