A case of recurrent cholangiocarcinoma responding to weekly paclitaxel

Naoki Sakurai, Takaho Okada, Hajime Iizawa

Research output: Contribution to journalArticlepeer-review


A 72-year-old male underwent right hepatic lobectomy and pancreatoduodenectomy due to extrahepatic bile duct cancer in October 2007, and multiple lung metastases were later detected by CT three months after surgery. We started treatment with administration of S-1 at 100 mg/body. The CT at the end of the five courses revealed the progression of the lung metastases. Therefore we tried GEM at 1, 600 mg/body. After six courses, CT revealed more progression of the recurrent tumors. We then changed the chemotherapy menu to weekly PTX at 130 mg/body. Three courses after the chemotherapy of PTX, CT showed remarkable regression of multiple lung metastases, and the serum levels of tumor marker CA19-9 were also reduced to within the normal range. This remarkable regression of metastases has been maintained for 6 months.

Original languageEnglish
Pages (from-to)1333-1335
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number7
Publication statusPublished - 2010 Jul
Externally publishedYes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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