A concise synthesis of 3-aroylflavonesviaLewis base 9-azajulolidine-catalyzed tandem acyl transfer–cyclization

Masahito Yoshida; Koya Saito; Yuta Fujino; Takayuki Doi

doi:10.1039/c2cc37015h

A concise synthesis of 3-aroylflavonesviaLewis base 9-azajulolidine-catalyzed tandem acyl transfer–cyclization

Masahito Yoshida, Koya Saito, Yuta Fujino, Takayuki Doi

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Lewis base-catalyzed tandem acyl transfer–cyclization of acylatedo-alkynoylphenols leading to 3-aroylflavones was developed. 9-Azajulolidine smoothly promoted the reaction of the aroyl derivatives at ambient temperature, and the structure-diversed synthesis of 3-aroylflavones with distinct substituents was achieved in moderate to excellent yields.

Original language	English
Pages (from-to)	11796-11798
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	96
DOIs	https://doi.org/10.1039/c2cc37015h
Publication status	Published - 2012 Nov 7

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "Lewis base-catalyzed tandem acyl transfer–cyclization of acylatedo-alkynoylphenols leading to 3-aroylflavones was developed. 9-Azajulolidine smoothly promoted the reaction of the aroyl derivatives at ambient temperature, and the structure-diversed synthesis of 3-aroylflavones with distinct substituents was achieved in moderate to excellent yields.",

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AU - Saito, Koya

AU - Fujino, Yuta

AU - Doi, Takayuki

PY - 2012/11/7

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AB - Lewis base-catalyzed tandem acyl transfer–cyclization of acylatedo-alkynoylphenols leading to 3-aroylflavones was developed. 9-Azajulolidine smoothly promoted the reaction of the aroyl derivatives at ambient temperature, and the structure-diversed synthesis of 3-aroylflavones with distinct substituents was achieved in moderate to excellent yields.

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A concise synthesis of 3-aroylflavonesviaLewis base 9-azajulolidine-catalyzed tandem acyl transfer–cyclization

Abstract

ASJC Scopus subject areas

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