@inproceedings{09d0e7f3a63243308592d981bba74c0d,
title = "A microfludic device with interdigitated array electrodes for detection of hormone active chemicals using genetically-engineered yeast cells",
abstract = "Endocrine disrupting chemicals that act like hormones is a potential hazard for human health. Therefore, it is necessary to develop a device that can detect easily hormone active chemicals. In this study, a microfludic device with some analytical chambers was fabricated for manipulating the yeast cells that were genetically engineered to respond to the presence of hormone active chemicals by synthesizing β-galactosidase (β-gal). Interdigitated array (IDA) electrodes with 40 electrode fingers were incorporated into the device for sensitive detection of the β-gal activity electrochemically, and hormone active chemicals were successfully detected by using the systems.",
keywords = "Hormone active chemical, IDA electrode, Microfluidic device, Two-hybrid assay system, β-gal activity",
author = "Kosuke Ino and Yusuke Kitagawa and Hitoshi Shiku and Masahiro Koide and Yoshiko Horiguchi and Tomoaki Itayama and Tomoyuki Yasukawa and Tomokazu Matsue",
year = "2009",
language = "English",
isbn = "9780979806421",
series = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "1623--1625",
booktitle = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
note = "13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 ; Conference date: 01-11-2009 Through 05-11-2009",
}
