A new approach to 3-substituted indoles through palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamines

Kiyofumi Inamoto; Tadataka Saito; Kou Hiroya; Takayuki Doi

doi:10.1055/s-0028-1087413

A new approach to 3-substituted indoles through palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamines

Kiyofumi Inamoto, Tadataka Saito, Kou Hiroya, Takayuki Doi

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)₂ (10 mol%)/Cu(OAc)₂ (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles.

Original language	English
Pages (from-to)	3157-3162
Number of pages	6
Journal	Synlett
Issue number	20
DOIs	https://doi.org/10.1055/s-0028-1087413
Publication status	Published - 2008 Dec 16

Keywords

Animations
C-H activation
Catalysis
Indoles
Palladium

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0028-1087413

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abstract = "Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)2 (10 mol%)/Cu(OAc)2 (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles.",

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AU - Inamoto, Kiyofumi

AU - Saito, Tadataka

AU - Hiroya, Kou

AU - Doi, Takayuki

PY - 2008/12/16

Y1 - 2008/12/16

N2 - Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)2 (10 mol%)/Cu(OAc)2 (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles.

AB - Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)2 (10 mol%)/Cu(OAc)2 (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles.

KW - Animations

KW - C-H activation

KW - Catalysis

KW - Indoles

KW - Palladium

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A new approach to 3-substituted indoles through palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamines

Abstract

Keywords

ASJC Scopus subject areas

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