A new aza-BODIPY based NIR region colorimetric and fluorescent chemodosimeter for fluoride

Bin Zou; Hui Liu; John Mack; Sisi Wang; Jiangwei Tian; Hua Lu; Zhifang Li; Zhen Shen

doi:10.1039/c4ra06416j

A new aza-BODIPY based NIR region colorimetric and fluorescent chemodosimeter for fluoride

Bin Zou, Hui Liu, John Mack, Sisi Wang, Jiangwei Tian, Hua Lu, Zhifang Li, Zhen Shen

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

The synthesis and characterization of a novel NIR region fluoride sensor, that makes use of the aza-boron-dipyrromethene (aza-BODIPY) fluorophore, is described. An arylmagnesium bromide was formed by reacting 4-bromophenol with a tert-butyldimethylsilyl protecting group and magnesium, which was then used to prepare the aza-BODIPY through a reaction with phthalonitrile. The unusually strong affinity between the fluoride anion and silicon is used to create a sensor dye, which exhibits a highly specific, rapid colorimetric and 'turn-off' fluorescence response for F^- in solution and in living HeLa cells. With F^-, there is enhanced intramolecular charge transfer within the S₁ state and this results in efficient nonradiative decay and hence in a marked decrease in fluorescence emission intensity. This journal is

Original language	English
Pages (from-to)	53864-53869
Number of pages	6
Journal	RSC Advances
Volume	4
Issue number	96
DOIs	https://doi.org/10.1039/c4ra06416j
Publication status	Published - 2014

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

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AU - Zou, Bin

AU - Liu, Hui

AU - Mack, John

AU - Wang, Sisi

AU - Tian, Jiangwei

AU - Lu, Hua

AU - Li, Zhifang

AU - Shen, Zhen

PY - 2014

Y1 - 2014

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A new aza-BODIPY based NIR region colorimetric and fluorescent chemodosimeter for fluoride

Abstract

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