A new method to evaluate pH at the interface between parasites and biomaterials

Gen Mayanagi, Koei Igarashi, Jumpei Washio, Kazuko Nakajo, Hitomi Domon-Tawaraya, Nobuhiro Takahashi

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Physiochemical assessment of the parasite-biomaterial interface is essential to develop new biomaterials. The purpose of this study was to develop a method to evaluate pH at the parasite-biomaterial interface and demonstrate physiochemical interaction at the interface. An experimental apparatus with a well for pH monitoring was made of acrylic resin with a bottom of test materials. The well was filled with Streptococcus mutans NCTC 10449, and an ion-sensitive field-effect transistor (ISFET) pH electrode was placed at an interface between bacterial cells and materials. The pH was monitored after the addition of 1% glucose at 37°C. The pH at the parasite-biomaterial interface was successfully monitored using the experimental apparatus with an ISFET pH electrode. This method could be useful to assess the pH at the parasite-biomaterial interface.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2011
PublisherSpringer Japan
Number of pages3
ISBN (Electronic)9784431540700
ISBN (Print)9784431540694
Publication statusPublished - 2012 Jan 1


  • Biomaterial
  • Ion-sensitive field-effect transistor pH electrode
  • Parasite
  • pH
  • Physiochemical interaction


Dive into the research topics of 'A new method to evaluate pH at the interface between parasites and biomaterials'. Together they form a unique fingerprint.

Cite this