TY - JOUR
T1 - A novel extraction method of fetal electrocardiogram from the composite abdominal signal
AU - Sato, Michiyoshi
AU - Kimura, Yoshitaka
AU - Chida, Shinichi
AU - Ito, Takuya
AU - Katayama, Norihiro
AU - Okamura, Kunihiro
AU - Nakao, Mitsuyuki
N1 - Funding Information:
Manuscript received March 14, 2005; revised June 3, 2006. This work was supported in part by Special Coordination Funds for Promoting Science and Technology and by the “Academic Frontiers” Project for Private Universities (Kansei Fukushi Research Center of Tohoku Fukushi University) through a matching fund subsidy from the Ministry of Education, Culture, Sports, Science and Technology of Japan. Additional support was provided by the Collaborative Research in Center for Interdisciplinary Research, Tohoku University. Asterisk indicates corresponding author.
PY - 2007/1
Y1 - 2007/1
N2 - In contrast to the ultrasonic measurement of fetal heart motion, the fetal electrocardiogram (ECG) provides clinically significant information concerning the electrophysiological state of a fetus. In this paper, a novel method for extracting the fetal ECG from abdominal composite signals is proposed. This method consists of the cancellation of the mother's ECG and blind source separation with the reference signal (BSSR). The cancellation of the mother's ECG component was performed by subtracting the linear combination of mutually orthogonal projections of the heart vector. The BSSR is a fixed-point algorithm, the Lagrange function of which includes the higher order cross-correlation between the extracted signal and the reference signal as the cost term rather than a constraint. This realizes the convexity of the Lagrange function in a simple form, which guarantees the convergence of the algorithm. By practical application, the proposed method has been shown to be able to extract the P and T waves in addition to the R wave. The reliability and accuracy of the proposed method was confirmed by comparing the extracted signals with the directly recorded ECG at the second stage of labor. The gestational age-dependency of the physiological parameters of the extracted fetal ECG also coincided well with that of the magnetocardiogram, which proves the clinical applicability of the proposed method.
AB - In contrast to the ultrasonic measurement of fetal heart motion, the fetal electrocardiogram (ECG) provides clinically significant information concerning the electrophysiological state of a fetus. In this paper, a novel method for extracting the fetal ECG from abdominal composite signals is proposed. This method consists of the cancellation of the mother's ECG and blind source separation with the reference signal (BSSR). The cancellation of the mother's ECG component was performed by subtracting the linear combination of mutually orthogonal projections of the heart vector. The BSSR is a fixed-point algorithm, the Lagrange function of which includes the higher order cross-correlation between the extracted signal and the reference signal as the cost term rather than a constraint. This realizes the convexity of the Lagrange function in a simple form, which guarantees the convergence of the algorithm. By practical application, the proposed method has been shown to be able to extract the P and T waves in addition to the R wave. The reliability and accuracy of the proposed method was confirmed by comparing the extracted signals with the directly recorded ECG at the second stage of labor. The gestational age-dependency of the physiological parameters of the extracted fetal ECG also coincided well with that of the magnetocardiogram, which proves the clinical applicability of the proposed method.
KW - Blind source separation with reference signal
KW - Fetal electrocardiogram
KW - P and T waves
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U2 - 10.1109/TBME.2006.883791
DO - 10.1109/TBME.2006.883791
M3 - Article
C2 - 17260855
AN - SCOPUS:33846350199
SN - 0018-9294
VL - 54
SP - 49
EP - 58
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 1
M1 - 9
ER -