A novel method of assessing carcinoma cell proliferation by biophoton emission

Motohiro Takeda; Yukina Tanno; Masaki Kobayashi; Masashi Usa; Noriaki Ohuchi; Susumu Satomi; Humio Inaba

doi:10.1016/S0304-3835(98)00064-0

A novel method of assessing carcinoma cell proliferation by biophoton emission

Motohiro Takeda, Yukina Tanno, Masaki Kobayashi, Masashi Usa, Noriaki Ohuchi, Susumu Satomi, Humio Inaba

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

Changes in the emission intensities of ultraweak biophoton emission during the cell proliferation of human carcinoma cell culture (TE9 cell line) were detected using a highly sensitive and low noise measurement apparatus coupled with a flow culture system. In the sampling period of 93 h, the biophoton emission intensity from the culture followed a similar course as that of the growth curve. Spectral analysis of the biophoton emission from the cell culture demonstrated a significant peak at around 530 nm. Our results suggest that the emission intensity mainly depends on the cell population and that this non-invasive technique has a potential role in cancer diagnosis.

Original language	English
Pages (from-to)	155-160
Number of pages	6
Journal	Cancer Letters
Volume	127
Issue number	1-2
DOIs	https://doi.org/10.1016/S0304-3835(98)00064-0
Publication status	Published - 1998 May 15

Keywords

Cancer
Cell proliferation
TE9
Ultraweak biophoton emission
Ultraweak chemiluminescence

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0304-3835(98)00064-0

Cite this

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title = "A novel method of assessing carcinoma cell proliferation by biophoton emission",

abstract = "Changes in the emission intensities of ultraweak biophoton emission during the cell proliferation of human carcinoma cell culture (TE9 cell line) were detected using a highly sensitive and low noise measurement apparatus coupled with a flow culture system. In the sampling period of 93 h, the biophoton emission intensity from the culture followed a similar course as that of the growth curve. Spectral analysis of the biophoton emission from the cell culture demonstrated a significant peak at around 530 nm. Our results suggest that the emission intensity mainly depends on the cell population and that this non-invasive technique has a potential role in cancer diagnosis.",

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T1 - A novel method of assessing carcinoma cell proliferation by biophoton emission

AU - Takeda, Motohiro

AU - Tanno, Yukina

AU - Kobayashi, Masaki

AU - Usa, Masashi

AU - Ohuchi, Noriaki

AU - Satomi, Susumu

AU - Inaba, Humio

PY - 1998/5/15

Y1 - 1998/5/15

N2 - Changes in the emission intensities of ultraweak biophoton emission during the cell proliferation of human carcinoma cell culture (TE9 cell line) were detected using a highly sensitive and low noise measurement apparatus coupled with a flow culture system. In the sampling period of 93 h, the biophoton emission intensity from the culture followed a similar course as that of the growth curve. Spectral analysis of the biophoton emission from the cell culture demonstrated a significant peak at around 530 nm. Our results suggest that the emission intensity mainly depends on the cell population and that this non-invasive technique has a potential role in cancer diagnosis.

AB - Changes in the emission intensities of ultraweak biophoton emission during the cell proliferation of human carcinoma cell culture (TE9 cell line) were detected using a highly sensitive and low noise measurement apparatus coupled with a flow culture system. In the sampling period of 93 h, the biophoton emission intensity from the culture followed a similar course as that of the growth curve. Spectral analysis of the biophoton emission from the cell culture demonstrated a significant peak at around 530 nm. Our results suggest that the emission intensity mainly depends on the cell population and that this non-invasive technique has a potential role in cancer diagnosis.

KW - Cancer

KW - Cell proliferation

KW - TE9

KW - Ultraweak biophoton emission

KW - Ultraweak chemiluminescence

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A novel method of assessing carcinoma cell proliferation by biophoton emission

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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