A 38-year-old man was found to show a well-defined oval-shaped homogeneous dense mass (20 × 30 mm) in the left upper lung field on chest X-ray. Left upper divisionectomy was performed under video-assisted thoracic surgery. Histology showed that the tumor cells had abundant eosinophilic granular cytoplasm, and were immunopositive for neuron-specific enolase, CD56, S-100 protein, and chromogranin. The proportion of Ki-67 positive cells was < 1%. An electron-microscopic examination showed many membrane-bound whorls in the cytoplasm. Although this was a very rare case presenting as an asymptomatic coin lesion, the histological features were the same as those demonstrated for granular cell tumor at common sites.
|Number of pages||3|
|Journal||Japanese Journal of Thoracic and Cardiovascular Surgery|
|Publication status||Published - 2003 Mar|
- Granular cell tumor
- Video-assisted thoracic surgery