TY - JOUR
T1 - A Sapecin Homologue of Holotrichia Diomphalia
T2 - Purification, Sequencing and Determination of Disulfide Pairs
AU - Lee, So
AU - Moon, Hyun
AU - Lee, Bok
AU - Kawabata, Shunichiro
AU - Natori, Shunji
AU - Kurata, Shoichiro
PY - 1995
Y1 - 1995
N2 - We purified and characterized a sapecin homologue, named holotricin 1, from the hemolymph of immunized larvae of a coleopteran insect, Holotrichia diomphalia. We determined its complete amino acid sequence and three disulfide pairs. Holotricin 1 consisted of 43 amino acid residues and showed potent antibacterial activity against gram-positive bacteria, but antibacterial activity against gram-negative bacteria was not obvious.
AB - We purified and characterized a sapecin homologue, named holotricin 1, from the hemolymph of immunized larvae of a coleopteran insect, Holotrichia diomphalia. We determined its complete amino acid sequence and three disulfide pairs. Holotricin 1 consisted of 43 amino acid residues and showed potent antibacterial activity against gram-positive bacteria, but antibacterial activity against gram-negative bacteria was not obvious.
KW - antibacterial protein
KW - insect
KW - sapecin
UR - http://www.scopus.com/inward/record.url?scp=0028923897&partnerID=8YFLogxK
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U2 - 10.1248/bpb.18.457
DO - 10.1248/bpb.18.457
M3 - Article
C2 - 7550103
AN - SCOPUS:0028923897
SN - 0918-6158
VL - 18
SP - 457
EP - 459
JO - Biological and Pharmaceutical Bulletin
JF - Biological and Pharmaceutical Bulletin
IS - 3
ER -