@article{0de39fb4f3694145a11917ac46f552d1,
title = "A seroepidemiologic study of Reston ebolavirus in swine in the Philippines",
abstract = "Background: Ebola viruses cause viral hemorrhagic fever in humans and non-human primates and are endemic in Africa. Reston ebolavirus (REBOV) has caused several epizootics in cynomolgus monkeys (Macaca fascicularis) but is not associated with any human disease. In late 2008, REBOV infections were identified in swine for the first time in the Philippines.Methods: A total of 215 swine sera collected at two REBOV-affected farms in 2008, in Pangasinan and Bulacan, were tested for the presence of REBOV-specific antibodies using multiple serodiagnosis systems. A total of 98 swine sera collected in a non-epizootic region, Tarlac, were also tested to clarify the prevalence of REBOV infection in the general swine population in the Philippines.Results: Some 70 % of swine sera at the affected farms were positive for REBOV antibodies in the multiple serodiagnosis systems. On the other hand, none of the swine sera collected in Tarlac showed positive reactions in any of the diagnosis systems.Conclusions: The high prevalence of REBOV infection in swine in the affected farms in 2008 suggests that swine is susceptible for REBOV infection. The multiple serological assays used in the study are thought to be useful for future surveillance of REOBV infection in swine in the Philippines.",
keywords = "Antibody, Philippines, Reston ebolavirus, Swine",
author = "Yusuke Sayama and Catalino Demetria and Mariko Saito and Azul, {Rachel R.} and Satoshi Taniguchi and Shuetsu Fukushi and Tomoki Yoshikawa and Itoe Iizuka and Tetsuya Mizutani and Ichiro Kurane and Malbas, {Fidelino F.} and Socorro Lupisan and Catbagan, {Davinio P.} and Animas, {Samuel B.} and Morales, {Rieldrin G.} and Lopez, {Emelinda L.} and Dazo, {Karen Rose C.} and Cruz, {Magdalena S.} and Remigio Olveda and Masayuki Saijo and Hitoshi Oshitani and Shigeru Morikawa",
note = "Funding Information: We gratefully acknowledge Ms Momoko Ogata at the National Institute of Infectious Diseases, Japan, and the staff of the Research Institute for Tropical Medicine and the Bureau of Animal Industry, the Philippines, for their technical assistance. We also acknowledge Dr. Tian Cheng Li at the National Institute of Infectious Diseases, Japan, for supplying the swine sera collected in Japan. We sincerely acknowledge Dr. Roger Hewson at the Centre for Emergency Preparedness and Response, Health Protection Agency, UK, for critical reading the manuscript. This work was supported in part by a grant-in-aid to S.M. from the Ministry of Health, Labor and Welfare of Japan (grants H22-shinkou-ippan-006) and to H.O. for The Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.",
year = "2012",
month = jun,
day = "18",
doi = "10.1186/1746-6148-8-82",
language = "English",
volume = "8",
journal = "BMC Veterinary Research",
issn = "1746-6148",
publisher = "BioMed Central Ltd.",
}
