A single-beat estimation method for emax directly based on linearity of ventricular elastance

Makoto Yoshizawa, Megumi Yokogawa, Akira Tanaka, Ken Ichi Abe, Hiroshi Takeda, Yoshifumi Saijo, Tomoyuki Yambe, Shin Ichi Nitta

Research output: Contribution to journalConference articlepeer-review


This paper has derived a new method for estimating the maximum ventricular elastance Emax by assuming that the following two assumptions are simultaneously established in a certain part of the ejection period: the ven-tricular elastance E(t) changes linearly with time and the dead volume V0 does not change. The method can estimate Emax in a single beat without any change in the cardiac load by measuring the ventricular pressure and either the ven-tricular volume or outflow. The method does not need to previously assign the approximation range of E(t) and does not include the recursive procedure to search for the peak time tmax that gives Emax. In an experiment in vivo, it could be ascertained that the method can derive the estimate of Emax roughly close to the true value.

Original languageEnglish
Pages (from-to)155
Number of pages1
JournalAnnual Reports of the Research Reactor Institute, Kyoto University
Publication statusPublished - 2001
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: 2001 Oct 252001 Oct 28


  • Cardiac function
  • Emax
  • End-systolic ventricular elastance
  • Estimation


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