Absolute configuration of 3,3′-dihydroxy-4,4′-biphenanthryl as determined by the stereochemistry of cyclic diester formation with 1,1′-binaphthyl-2,2′-dicarboxylic acid

Nobuyuki Koike, Tetsutaro Hattori, Sotaro Miyano

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Condensation of racemic 3,3′-dihydroxy-4,4′-biphenanthryl [(±)-2] with (R)-1,1′-binaphthyl-2,2′-dicarboxylic acid dichloride (5) allows cyclization of only (-)-2 to give the 12-membered cyclic diester (7), the absolute configuration of which can be assigned (R,R) from steric reasons. Thus, absolute stereochemistry of (-)-2 is determined to be (R).

Original languageEnglish
Pages (from-to)1899-1900
Number of pages2
JournalTetrahedron: Asymmetry
Volume5
Issue number10
DOIs
Publication statusPublished - 1994 Oct

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