TY - JOUR
T1 - Absorption and metabolism of γ-oryzanol, a characteristic functional ingredient in rice bran
AU - Sawada, Kazue
AU - Rahmania, Halida
AU - Matsuki, Midori
AU - Hashimoto, Hiroyuki
AU - Ito, Junya
AU - Miyazawa, Teruo
AU - Nakagawa, Kiyotaka
N1 - Funding Information:
This work was supported in part by the Research and Development Support Project for Pioneering Industrial Technology by Wakayama Prefectural Government, Japan and the development program of promising enterprises by Public Interest Incorporated Foundation Wakayama Industry Promotion Foundation, Japan. This work was also supported in part by the Japan Society for the Promotion of Science (JSPS) through JSPS Core-to-Core Program (Advanced Research Networks) entitled “Establishment of international agricultural immunology research-core for a quantum improvement in food safety.”
Publisher Copyright:
© 2019, Center for Academic Publications Japan. All rights reserved.
PY - 2019
Y1 - 2019
N2 - γ-Oryzanol (OZ), a functional substance found in rice bran, consists of multiple molecular species. In both in vitro and in vivo studies, the researches exploring the various function of rice bran OZ have been conducted for a long time, and it has become clear that OZ has a lot of pharmaceutical activities. It is assumed that each type of OZ molecular species may have different effects. In contrast, the profile behaviour of OZ inside the body has not been fully understood. This article reviews the previous studies about the digestion, absorption, metabolism, and effects of rice bran OZ and also introduces the new method to evaluate the OZ metabolic fate by using high-performance liquid chromatography (HPLC) combined with tandem mass-spectrometry (MS/MS) which has higher selectivity and sensitivity.
AB - γ-Oryzanol (OZ), a functional substance found in rice bran, consists of multiple molecular species. In both in vitro and in vivo studies, the researches exploring the various function of rice bran OZ have been conducted for a long time, and it has become clear that OZ has a lot of pharmaceutical activities. It is assumed that each type of OZ molecular species may have different effects. In contrast, the profile behaviour of OZ inside the body has not been fully understood. This article reviews the previous studies about the digestion, absorption, metabolism, and effects of rice bran OZ and also introduces the new method to evaluate the OZ metabolic fate by using high-performance liquid chromatography (HPLC) combined with tandem mass-spectrometry (MS/MS) which has higher selectivity and sensitivity.
KW - Absorption and metabolism
KW - HPLC-MS/MS
KW - Rice bran oil
KW - γ-oryzanol
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U2 - 10.3177/jnsv.65.S180
DO - 10.3177/jnsv.65.S180
M3 - Article
C2 - 31619625
AN - SCOPUS:85073410743
SN - 0301-4800
VL - 65
SP - S180-S184
JO - Journal of Nutritional Science and Vitaminology
JF - Journal of Nutritional Science and Vitaminology
ER -