Acquiring toxicity of a newt, Cynops orientalis

Dietrich Mebs, Mari Yotsu-Yamashita

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Tetrodotoxin (TTX) contents of wild-caught Chinese red-bellied newts, Cynops orientalis, and their offspring captive-reared from eggs to metamorphosed juveniles, were analysed using post-column LC-fluorescent detection (LC-FLD) and high resolution hydrophilic interaction liquid chromatography/mass spectrometry (HR-HILIC-LC/MS). TTX was detected in the parent newts and their eggs, but not in the larvae and juveniles raised under artificial condition over 20 months. However, juveniles reared in the presence of their parents, contained TTX-concentrations up to 8.05 μg/g. The origin of TTX may be implied from a close connection between the parents and their offspring.

Original languageEnglish
Pages (from-to)32-35
Number of pages4
Publication statusPublished - 2021 Jul 30


  • Cynops orientalis
  • LC-FLD
  • Newt
  • Tetrodotoxin
  • Toxin acquisition


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