Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope

Masato Tsutsui; Takeyuki Matsuguchi; Hiroyuki Tsutsui; Shingo Yoshihara; Kunihiko Yamamoto; Hiroaki Shimokawa; Shuichi Okamatsu; Ryuichi Hisanou; Tetsuhiko Yoshida

doi:10.1536/ihj.33.875

Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope

Masato Tsutsui, Takeyuki Matsuguchi, Hiroyuki Tsutsui, Shingo Yoshihara, Kunihiko Yamamoto, Hiroaki Shimokawa, Shuichi Okamatsu, Ryuichi Hisanou, Tetsuhiko Yoshida

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

We observed 2 cases of repeated episodes of syncope after alcohol ingestion. Both patients were light drinkers and had carotid sinus hypersensitivity. In both cases, alcohol loading tests repeatedly induced sinus bradycardia and hypotension 1.0-1.5 hours after drinking alcohol. Atropine was effective in improving symptoms. A loading test using a glucose solution of equivalent osmolarity and volume was negative. Acute alcohol ingestion usually increases heart rate with variable effects on blood pressure. However, our 2 cases exhibited unusual alcohol-induced sinus bradycardia and hypotension, suggesting a paradoxical increase in parasympathetic activity and/or decrease in sympathetic activity.

Original language	English
Pages (from-to)	875-879
Number of pages	5
Journal	Japanese Heart Journal
Volume	33
Issue number	6
DOIs	https://doi.org/10.1536/ihj.33.875
Publication status	Published - 1992

Keywords

Alcohol
Bradycardia
Hypotension
Syncope

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1536/ihj.33.875

Cite this

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title = "Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope",

abstract = "We observed 2 cases of repeated episodes of syncope after alcohol ingestion. Both patients were light drinkers and had carotid sinus hypersensitivity. In both cases, alcohol loading tests repeatedly induced sinus bradycardia and hypotension 1.0-1.5 hours after drinking alcohol. Atropine was effective in improving symptoms. A loading test using a glucose solution of equivalent osmolarity and volume was negative. Acute alcohol ingestion usually increases heart rate with variable effects on blood pressure. However, our 2 cases exhibited unusual alcohol-induced sinus bradycardia and hypotension, suggesting a paradoxical increase in parasympathetic activity and/or decrease in sympathetic activity.",

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AU - Tsutsui, Masato

AU - Matsuguchi, Takeyuki

AU - Tsutsui, Hiroyuki

AU - Yoshihara, Shingo

AU - Yamamoto, Kunihiko

AU - Shimokawa, Hiroaki

AU - Okamatsu, Shuichi

AU - Hisanou, Ryuichi

AU - Yoshida, Tetsuhiko

PY - 1992

Y1 - 1992

N2 - We observed 2 cases of repeated episodes of syncope after alcohol ingestion. Both patients were light drinkers and had carotid sinus hypersensitivity. In both cases, alcohol loading tests repeatedly induced sinus bradycardia and hypotension 1.0-1.5 hours after drinking alcohol. Atropine was effective in improving symptoms. A loading test using a glucose solution of equivalent osmolarity and volume was negative. Acute alcohol ingestion usually increases heart rate with variable effects on blood pressure. However, our 2 cases exhibited unusual alcohol-induced sinus bradycardia and hypotension, suggesting a paradoxical increase in parasympathetic activity and/or decrease in sympathetic activity.

AB - We observed 2 cases of repeated episodes of syncope after alcohol ingestion. Both patients were light drinkers and had carotid sinus hypersensitivity. In both cases, alcohol loading tests repeatedly induced sinus bradycardia and hypotension 1.0-1.5 hours after drinking alcohol. Atropine was effective in improving symptoms. A loading test using a glucose solution of equivalent osmolarity and volume was negative. Acute alcohol ingestion usually increases heart rate with variable effects on blood pressure. However, our 2 cases exhibited unusual alcohol-induced sinus bradycardia and hypotension, suggesting a paradoxical increase in parasympathetic activity and/or decrease in sympathetic activity.

KW - Alcohol

KW - Bradycardia

KW - Hypotension

KW - Syncope

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Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope

Abstract

Keywords

ASJC Scopus subject areas

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