TY - JOUR
T1 - American College of Rheumatology and the European League Against Rheumatism classification criteria for IgG4-related disease
T2 - an update for radiologists
AU - Ren, Hainan
AU - Mori, Naoko
AU - Sato, Satoko
AU - Mugikura, Shunji
AU - Masamune, Atsushi
AU - Takase, Kei
N1 - Funding Information:
This work was supported by MHLW Research Program on Rare and Intractable Diseases Grant Number JPMH20FC1040.
Publisher Copyright:
© 2022, The Author(s) under exclusive licence to Japan Radiological Society.
PY - 2022/9
Y1 - 2022/9
N2 - IgG4-related disease (IgG4-RD) is an immune-mediated, multiorgan, chronic inflammatory disease. The three-step classification criteria proposed in 2019 by the American College of Rheumatology and the European League Against Rheumatism (ACR/EULAR) encompass a wide range of clinical, radiological, serological, and histopathological findings. The ACR/EULAR proposed a three-step classification process, i.e., entry step, exclusion step, and scoring system. Radiologists need to know that the radiological findings observed in the five domains of the lacrimal and salivary glands, chest, pancreas and biliary ducts, kidney, and retroperitoneum are independently weighted with different points in the scoring system. A total score < 20 points indicates that the patient should not be classified as having IgG4-RD; conversely, a total score ≥ 20 points indicates that the patient should be classified as having IgG4-RD. In this review, the 2019 ACR/EULAR classification criteria are discussed, focusing on the interpretation of each radiological item, with the aim of applying them to the diagnosis of IgG4-RD in clinical practice.
AB - IgG4-related disease (IgG4-RD) is an immune-mediated, multiorgan, chronic inflammatory disease. The three-step classification criteria proposed in 2019 by the American College of Rheumatology and the European League Against Rheumatism (ACR/EULAR) encompass a wide range of clinical, radiological, serological, and histopathological findings. The ACR/EULAR proposed a three-step classification process, i.e., entry step, exclusion step, and scoring system. Radiologists need to know that the radiological findings observed in the five domains of the lacrimal and salivary glands, chest, pancreas and biliary ducts, kidney, and retroperitoneum are independently weighted with different points in the scoring system. A total score < 20 points indicates that the patient should not be classified as having IgG4-RD; conversely, a total score ≥ 20 points indicates that the patient should be classified as having IgG4-RD. In this review, the 2019 ACR/EULAR classification criteria are discussed, focusing on the interpretation of each radiological item, with the aim of applying them to the diagnosis of IgG4-RD in clinical practice.
KW - CT
KW - Classification criteria
KW - FDG-PET/CT
KW - IgG4-related disease
KW - MRI
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U2 - 10.1007/s11604-022-01282-1
DO - 10.1007/s11604-022-01282-1
M3 - Review article
C2 - 35474439
AN - SCOPUS:85128865083
SN - 1867-1071
VL - 40
SP - 876
EP - 893
JO - Japanese Journal of Radiology
JF - Japanese Journal of Radiology
IS - 9
ER -