TY - JOUR
T1 - Amino acid-induced responses in CNS neurones of normal mouse and wriggle mouse sagami
AU - Furukawa, Katsutoshi
AU - Abe, Yumiko
AU - Osawa, Nobutaka
AU - Ohmura, Michio
AU - Akaike, Norio
PY - 1994/7
Y1 - 1994/7
N2 - Amino acid-induced responses and their regional heterogeneities in the motor cortical and hippocampal (CA1) neurones of normal mouse and Wriggle Mouse Sagami (WMS) were studied by conventional patch-clamp techniques. There were no differences in the current densities and EC50s of glutamate-, β-amino butyric acid (GABA)-, and glycine-induced responses between the two groups of mice. In both types of mice, the GABA-induced current density of cortical neurones was higher and EC50 was lower than in hippocampal neurones, whereas the responses induced by glycine and glutamate did not show any difference.
AB - Amino acid-induced responses and their regional heterogeneities in the motor cortical and hippocampal (CA1) neurones of normal mouse and Wriggle Mouse Sagami (WMS) were studied by conventional patch-clamp techniques. There were no differences in the current densities and EC50s of glutamate-, β-amino butyric acid (GABA)-, and glycine-induced responses between the two groups of mice. In both types of mice, the GABA-induced current density of cortical neurones was higher and EC50 was lower than in hippocampal neurones, whereas the responses induced by glycine and glutamate did not show any difference.
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U2 - 10.1097/00001756-199407000-00030
DO - 10.1097/00001756-199407000-00030
M3 - Article
C2 - 7948855
AN - SCOPUS:0028142116
SN - 0959-4965
VL - 5
SP - 1530
EP - 1532
JO - NeuroReport
JF - NeuroReport
IS - 12
ER -