An unusual spirocyclic isopimarane diterpenoid and other isopimarane diterpenoids from fruiting bodies of Xylaria polymorpha

Yoshihito Shiono; Norika Matsui; Takayuki Imaizumi; Takuya Koseki; Tetsuya Murayama; Eunsang Kwon; Tomomi Abe; Ken Ichi Kimura

doi:10.1016/j.phytol.2013.05.008

An unusual spirocyclic isopimarane diterpenoid and other isopimarane diterpenoids from fruiting bodies of Xylaria polymorpha

Yoshihito Shiono, Norika Matsui, Takayuki Imaizumi, Takuya Koseki, Tetsuya Murayama, Eunsang Kwon, Tomomi Abe, Ken Ichi Kimura

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Two new isopimarane-type diterpenes, spiropolin A (1) and myrocin E (3), were isolated from Xylaria polymorpha together with the known compound, myrocin D (2), in the course of a screening of the fruiting bodies of X. polymorpha. Their structures were determined on the basis of spectroscopic analysis, chemical conversion and X-ray analysis. Spiropolin A (1) restored the growth inhibition caused by the hyperactivated Ca2+-signaling in mutant yeast.

Original language	English
Pages (from-to)	439-443
Number of pages	5
Journal	Phytochemistry Letters
Volume	6
Issue number	3
DOIs	https://doi.org/10.1016/j.phytol.2013.05.008
Publication status	Published - 2013

Keywords

Fruiting body
Xylaria polymorpha

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10.1016/j.phytol.2013.05.008

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abstract = "Two new isopimarane-type diterpenes, spiropolin A (1) and myrocin E (3), were isolated from Xylaria polymorpha together with the known compound, myrocin D (2), in the course of a screening of the fruiting bodies of X. polymorpha. Their structures were determined on the basis of spectroscopic analysis, chemical conversion and X-ray analysis. Spiropolin A (1) restored the growth inhibition caused by the hyperactivated Ca2+-signaling in mutant yeast.",

keywords = "Fruiting body, Xylaria polymorpha",

author = "Yoshihito Shiono and Norika Matsui and Takayuki Imaizumi and Takuya Koseki and Tetsuya Murayama and Eunsang Kwon and Tomomi Abe and Kimura, {Ken Ichi}",

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doi = "10.1016/j.phytol.2013.05.008",

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volume = "6",

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journal = "Phytochemistry Letters",

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T1 - An unusual spirocyclic isopimarane diterpenoid and other isopimarane diterpenoids from fruiting bodies of Xylaria polymorpha

AU - Shiono, Yoshihito

AU - Matsui, Norika

AU - Imaizumi, Takayuki

AU - Koseki, Takuya

AU - Murayama, Tetsuya

AU - Kwon, Eunsang

AU - Abe, Tomomi

AU - Kimura, Ken Ichi

PY - 2013

Y1 - 2013

N2 - Two new isopimarane-type diterpenes, spiropolin A (1) and myrocin E (3), were isolated from Xylaria polymorpha together with the known compound, myrocin D (2), in the course of a screening of the fruiting bodies of X. polymorpha. Their structures were determined on the basis of spectroscopic analysis, chemical conversion and X-ray analysis. Spiropolin A (1) restored the growth inhibition caused by the hyperactivated Ca2+-signaling in mutant yeast.

AB - Two new isopimarane-type diterpenes, spiropolin A (1) and myrocin E (3), were isolated from Xylaria polymorpha together with the known compound, myrocin D (2), in the course of a screening of the fruiting bodies of X. polymorpha. Their structures were determined on the basis of spectroscopic analysis, chemical conversion and X-ray analysis. Spiropolin A (1) restored the growth inhibition caused by the hyperactivated Ca2+-signaling in mutant yeast.

KW - Fruiting body

KW - Xylaria polymorpha

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DO - 10.1016/j.phytol.2013.05.008

M3 - Article

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SN - 1874-3900

VL - 6

SP - 439

EP - 443

JO - Phytochemistry Letters

JF - Phytochemistry Letters

IS - 3

ER -

An unusual spirocyclic isopimarane diterpenoid and other isopimarane diterpenoids from fruiting bodies of Xylaria polymorpha

Abstract

Keywords

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