Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident

Yasuyuki Abe; Hideaki Yamashiro; Yasushi Kino; Toshinori Oikawa; Masatoshi Suzuki; Yusuke Urushihara; Yoshikazu Kuwahara; Motoko Morimoto; Jin Kobayashi; Tsutomu Sekine; Tomokazu Fukuda; Emiko Isogai; Manabu Fukumoto

doi:10.1007/978-981-13-8218-5_9

Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident

Yasuyuki Abe, Hideaki Yamashiro, Yasushi Kino, Toshinori Oikawa, Masatoshi Suzuki, Yusuke Urushihara, Yoshikazu Kuwahara, Motoko Morimoto, Jin Kobayashi, Tsutomu Sekine, Tomokazu Fukuda, Emiko Isogai, Manabu Fukumoto

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

In order to understand the effect of chronic exposure to low-dose-rate radiation on female fertilities and the risk of heritable genetic effects on domestic animals after the Fukushima Daiichi Nuclear Power Plant (FNPP) accident, we assessed the developmental ability of oocytes, and examined the histological characters and structure of ovaries. We showed that potentially viable oocytes could be collected from the ovary of abandoned cattle in the ex-evacuation zone set within a 20-km radius from FNPP, resulting in production of the morphologically normal calves following in vitro culture and embryo transfer. The proliferation of cattle ovarian granulosa cells was confirmed by expression of Ki-67. Apoptosis of oocytes and granulosa cells was few determined by the TUNEL assay. In addition, porcine and inobuta oocytes had the abilities of in vitro maturation. These results suggest that chronic radiation exposure associated with the FNPP accident may have little effect, if any, on the female fertilities of domestic animals.

Original language	English
Title of host publication	Low-Dose Radiation Effects on Animals and Ecosystems
Subtitle of host publication	Long-Term Study on the Fukushima Nuclear Accident
Publisher	Springer Singapore
Pages	113-123
Number of pages	11
ISBN (Electronic)	9789811382185
ISBN (Print)	9789811382178
DOIs	https://doi.org/10.1007/978-981-13-8218-5_9
Publication status	Published - 2019 Jan 1

Keywords

Cattle
Fertility
Fukushima Daiichi Nuclear Power Plant
Oocyte
Ovary
Radioactive cesium

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10.1007/978-981-13-8218-5_9

Cite this

Abe, Y., Yamashiro, H., Kino, Y., Oikawa, T., Suzuki, M., Urushihara, Y., Kuwahara, Y., Morimoto, M., Kobayashi, J., Sekine, T., Fukuda, T., Isogai, E., & Fukumoto, M. (2019). Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident. In Low-Dose Radiation Effects on Animals and Ecosystems: Long-Term Study on the Fukushima Nuclear Accident (pp. 113-123). Springer Singapore. https://doi.org/10.1007/978-981-13-8218-5_9

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title = "Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident",

abstract = "In order to understand the effect of chronic exposure to low-dose-rate radiation on female fertilities and the risk of heritable genetic effects on domestic animals after the Fukushima Daiichi Nuclear Power Plant (FNPP) accident, we assessed the developmental ability of oocytes, and examined the histological characters and structure of ovaries. We showed that potentially viable oocytes could be collected from the ovary of abandoned cattle in the ex-evacuation zone set within a 20-km radius from FNPP, resulting in production of the morphologically normal calves following in vitro culture and embryo transfer. The proliferation of cattle ovarian granulosa cells was confirmed by expression of Ki-67. Apoptosis of oocytes and granulosa cells was few determined by the TUNEL assay. In addition, porcine and inobuta oocytes had the abilities of in vitro maturation. These results suggest that chronic radiation exposure associated with the FNPP accident may have little effect, if any, on the female fertilities of domestic animals.",

keywords = "Cattle, Fertility, Fukushima Daiichi Nuclear Power Plant, Oocyte, Ovary, Radioactive cesium",

author = "Yasuyuki Abe and Hideaki Yamashiro and Yasushi Kino and Toshinori Oikawa and Masatoshi Suzuki and Yusuke Urushihara and Yoshikazu Kuwahara and Motoko Morimoto and Jin Kobayashi and Tsutomu Sekine and Tomokazu Fukuda and Emiko Isogai and Manabu Fukumoto",

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year = "2019",

month = jan,

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doi = "10.1007/978-981-13-8218-5\_9",

language = "English",

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Abe, Y, Yamashiro, H, Kino, Y, Oikawa, T, Suzuki, M, Urushihara, Y, Kuwahara, Y, Morimoto, M, Kobayashi, J, Sekine, T, Fukuda, T, Isogai, E & Fukumoto, M 2019, Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident. in Low-Dose Radiation Effects on Animals and Ecosystems: Long-Term Study on the Fukushima Nuclear Accident. Springer Singapore, pp. 113-123. https://doi.org/10.1007/978-981-13-8218-5_9

Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident. / Abe, Yasuyuki; Yamashiro, Hideaki; Kino, Yasushi et al.
Low-Dose Radiation Effects on Animals and Ecosystems: Long-Term Study on the Fukushima Nuclear Accident. Springer Singapore, 2019. p. 113-123.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident

AU - Abe, Yasuyuki

AU - Yamashiro, Hideaki

AU - Kino, Yasushi

AU - Oikawa, Toshinori

AU - Suzuki, Masatoshi

AU - Urushihara, Yusuke

AU - Kuwahara, Yoshikazu

AU - Morimoto, Motoko

AU - Kobayashi, Jin

AU - Sekine, Tsutomu

AU - Fukuda, Tomokazu

AU - Isogai, Emiko

AU - Fukumoto, Manabu

PY - 2019/1/1

Y1 - 2019/1/1

N2 - In order to understand the effect of chronic exposure to low-dose-rate radiation on female fertilities and the risk of heritable genetic effects on domestic animals after the Fukushima Daiichi Nuclear Power Plant (FNPP) accident, we assessed the developmental ability of oocytes, and examined the histological characters and structure of ovaries. We showed that potentially viable oocytes could be collected from the ovary of abandoned cattle in the ex-evacuation zone set within a 20-km radius from FNPP, resulting in production of the morphologically normal calves following in vitro culture and embryo transfer. The proliferation of cattle ovarian granulosa cells was confirmed by expression of Ki-67. Apoptosis of oocytes and granulosa cells was few determined by the TUNEL assay. In addition, porcine and inobuta oocytes had the abilities of in vitro maturation. These results suggest that chronic radiation exposure associated with the FNPP accident may have little effect, if any, on the female fertilities of domestic animals.

AB - In order to understand the effect of chronic exposure to low-dose-rate radiation on female fertilities and the risk of heritable genetic effects on domestic animals after the Fukushima Daiichi Nuclear Power Plant (FNPP) accident, we assessed the developmental ability of oocytes, and examined the histological characters and structure of ovaries. We showed that potentially viable oocytes could be collected from the ovary of abandoned cattle in the ex-evacuation zone set within a 20-km radius from FNPP, resulting in production of the morphologically normal calves following in vitro culture and embryo transfer. The proliferation of cattle ovarian granulosa cells was confirmed by expression of Ki-67. Apoptosis of oocytes and granulosa cells was few determined by the TUNEL assay. In addition, porcine and inobuta oocytes had the abilities of in vitro maturation. These results suggest that chronic radiation exposure associated with the FNPP accident may have little effect, if any, on the female fertilities of domestic animals.

KW - Cattle

KW - Fertility

KW - Fukushima Daiichi Nuclear Power Plant

KW - Oocyte

KW - Ovary

KW - Radioactive cesium

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U2 - 10.1007/978-981-13-8218-5_9

DO - 10.1007/978-981-13-8218-5_9

M3 - Chapter

AN - SCOPUS:85150582189

SN - 9789811382178

SP - 113

EP - 123

BT - Low-Dose Radiation Effects on Animals and Ecosystems

PB - Springer Singapore

ER -

Analysis of Ovaries and Fertilities in Domestic Animals Affected by the Fukushima Daiichi Nuclear Power Plant Accident

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Keywords

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