TY - JOUR
T1 - Antibacterial effect of thiocyanate substituted poly(vinyl chloride)
AU - Kameda, Tomohito
AU - Ono, Masahiko
AU - Grause, Guido
AU - Mizoguchi, Tadaaki
AU - Yoshioka, Toshiaki
PY - 2011/9
Y1 - 2011/9
N2 - Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.
AB - Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.
KW - Bacterial adhesion
KW - Nucleophilic substitution: Thiocyanate
KW - Poly(vinyl chloride)
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U2 - 10.1007/s10965-010-9492-3
DO - 10.1007/s10965-010-9492-3
M3 - Article
AN - SCOPUS:80053385981
SN - 1022-9760
VL - 18
SP - 945
EP - 947
JO - Journal of Polymer Research
JF - Journal of Polymer Research
IS - 5
ER -