@article{b5bc63aa861e4d6cb18e8237204bb256,
title = "Application of high pressure, induced by water freezing, to the direct asymmetric aldol reaction",
abstract = "High pressure, induced by water freezing, has been successfully applied to the direct catalytic asymmetric aldol reaction, in which higher yield and better enantioselectivity can be realized than in the reaction at room temperature under 0.1MPa.",
keywords = "Asymmetric reaction, Direct aldol reaction, High pressure, Organocatalyst, Proline",
author = "Yujiro Hayashi and Wataru Tsuboi and Mitsuru Shoji and Noriyuki Suzuki",
note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research on Priority Areas (A) 'Exploitation of Multi-Element Cyclic Molecules' from the Ministry of Education, Culture, Sports, Science and Technology, Japan. Y. H. thanks Dr. Kiyoshi Hayakawa at the Kyoto Prefectural Comprehensive Center for small and medium enterprises for instruction concerning the pressure induced by water freezing.",
year = "2004",
month = may,
day = "24",
doi = "10.1016/j.tetlet.2004.03.190",
language = "English",
volume = "45",
pages = "4353--4356",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd.",
number = "22",
}