@inbook{ce01b39870b64de8bf3f9f289973f46e,
title = "Application of optogenetics in epilepsy research",
abstract = "Epilepsy is a disease characterized by seizures arising from paroxysmal and self-limited hypersynchrony of neurons. However, the mechanism by which the normal brain develops epilepsy, which involves a chronic process of structural and morphological changes known as epileptogenesis, is not fully understood. Optogenetics involves the use of genetic engineering and optics to monitor or control nerve cell activity. Compared to classical electrophysiological experiments, the application of optogenetics in epilepsy research has many advantages because it allows selective photic stimulation of cell types and electrical observation without introducing artifacts.",
keywords = "Animal model, Benign and chronic disease, Epilepsy, Ethical issue, Seizure",
author = "Osawa, {Shin Ichiro} and Teiji Tominaga",
note = "Funding Information: This work was supported by JSPS KAKENHI Grant Number 18 K08960, JERF TENKAN 18003 and The Clinical Research Promotion Program for Young Investigators of Tohoku University Hospital 2018. Publisher Copyright: {\textcopyright} Springer Nature Singapore Pte Ltd. 2021.",
year = "2021",
doi = "10.1007/978-981-15-8763-4_39",
language = "English",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "557--562",
booktitle = "Advances in Experimental Medicine and Biology",
}