Artificial-cellular computing

Shin Ichiro M. Nomura, Tsutomu Hamada

Research output: Contribution to journalArticlepeer-review


This paper describes a compelling method to make a wet-computing system based on artificial cell models. The discrete system is inspired by real cellchemicalinformationprocessing. Liposomes, whicharesmallvesicles of phospholipid bilayer membranes, have been established as the basement architecture of artificial cell models that can safely entrap enzymes, proteins, genes and substrates. Recently, biochemical reactions such as the gene expression system are incorporated within the liposome. Such liposome conditions can be "operated" by some specific physico-chemical triggers. Here, the possibility and real examples of the artificial cellular model and their operation as computation elements have been described.

Original languageEnglish
Pages (from-to)87-102
Number of pages16
JournalInternational Journal of Unconventional Computing
Issue number1
Publication statusPublished - 2009


  • Artificial cell model
  • Enzyme reaction
  • Gene expression
  • Lipid bilayer membrane
  • Liposome


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