TY - JOUR
T1 - Aspergillus oryzae palB(ory) encodes a calpain-like protease
T2 - Homology to Emericella nidulans PalB and conservation of functional regions
AU - Futai, Eugene
AU - Sorimachi, Hiroyuki
AU - Jeong, Seon Yong
AU - Kitamoto, Katsuhiko
AU - Ishiura, Shoichi
AU - Suzuki, Koichi
PY - 1999
Y1 - 1999
N2 - We have cloned and sequenced genomic DNA of Aspergillus oryzae palB(ory), orthologue of Emericella nidulans palB, which encodes a calpain- like protease modulating a signal transduction pathway during alkaline adaptation. The deduced amino acid sequence of PalB(ory) is 70.0% identical to PalB over its entire length. The regions with high similarity revealed possible domains important for their function. This is the first step towards understanding the alkaline adaptation mechanism of A. oryzae, which would be very useful in the fermentation industry.
AB - We have cloned and sequenced genomic DNA of Aspergillus oryzae palB(ory), orthologue of Emericella nidulans palB, which encodes a calpain- like protease modulating a signal transduction pathway during alkaline adaptation. The deduced amino acid sequence of PalB(ory) is 70.0% identical to PalB over its entire length. The regions with high similarity revealed possible domains important for their function. This is the first step towards understanding the alkaline adaptation mechanism of A. oryzae, which would be very useful in the fermentation industry.
KW - Alkaline adaptation
KW - Aspergillus oryzae
KW - Calpain
KW - palB homologue
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U2 - 10.1016/S1389-1723(99)80223-0
DO - 10.1016/S1389-1723(99)80223-0
M3 - Article
AN - SCOPUS:0032741731
SN - 1389-1723
VL - 88
SP - 438
EP - 440
JO - Journal of Bioscience and Bioengineering
JF - Journal of Bioscience and Bioengineering
IS - 4
ER -