Assessing the extent of breast cancer using multidetector row helical computed tomography

Kei Takase, Akihiko Furuta, Narumi Harada, Toru Takahashi, Kazumasa Igarashi, Yoshihiro Chiba, Kenichi Haga, Shoki Takahashi

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


OBJECTIVE: The aim of the study was to evaluate the usefulness of multidetector row helical computed tomography (MD-CT) in assessing the local extent of breast cancer. METHODS: Seventy-five breast cancer patients were examined using MD-CT with scanning performed in the supine position at 1-mm collimation. The extent of the breast tumors determined using CT was compared with that based on histopathologic mapping with continuous 5-mm slices. RESULTS: The CT evaluation of the maximum diameter of the extent of breast cancer was much better correlated with the histopathologic diagnosis (correlation coefficient = 0.90) than the pre-CT diagnosis (correlation coefficient = 0.46). Computed tomography correctly detected mammographically and clinically occult cancer other than the index lesion in 14 of 15 patients. The sensitivity, specificity, and accuracy in the diagnosis of the additional lesions were 93.3%, 98.3%, and 97.3%, respectively. Because the images were obtained in the supine position, they were useful for surgical planning. CONCLUSION: The extent of breast cancer can be determined accurately using MD-CT.

Original languageEnglish
Pages (from-to)479-485
Number of pages7
JournalJournal of Computer Assisted Tomography
Issue number3
Publication statusPublished - 2006


  • 3-Dimensional
  • Breast
  • Clinical effectiveness
  • Computed tomography
  • Helical


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