Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders

Hiroshi Komatsu; Takashi Ono; Yoshinori Maita; Yusuke Ishida; Tatsuo Kikuchi; Takahiro Maki; Satoshi Hase; Hisakazu Sakurai; Akiko Oba; Osamu Teshirogi; Akira Suzuki; Yasuko Mori; Chikako Shoji; Akira Fujita; Sachiko Takahashi; Takayuki Ebina; Shinya Ozaki; Ryuta Honma; Hiroaki Tomita; Yoshihisa Kakuto

doi:10.2147/NDT.S280485

Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders

Hiroshi Komatsu, Takashi Ono, Yoshinori Maita, Yusuke Ishida, Tatsuo Kikuchi, Takahiro Maki, Satoshi Hase, Hisakazu Sakurai, Akiko Oba, Osamu Teshirogi, Akira Suzuki, Yasuko Mori, Chikako Shoji, Akira Fujita, Sachiko Takahashi, Takayuki Ebina, Shinya Ozaki, Ryuta Honma, Hiroaki Tomita, Yoshihisa Kakuto

Miyagi Psychiatric Center

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Purpose: Self-stigma negatively influences self-esteem, quality of life, self-efficacy, treatment adherence, and recovery in psychiatric patients. By revealing personality traits that influence self-stigma, we can gain useful knowledge for the management of self-stigma. A previous meta-analysis indicated that patients with schizophrenia have higher scores on the Autism-Spectrum Quotient (AQ) than healthy controls. However, the relationship between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders remains unclear. Therefore, the present study aimed to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Patients and Methods: We recruited 127 patients with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, and delusional disorder). We assessed participants’ self-stigma and autistic symptoms using the Internalized Stigma for Mental Illness (ISMI) scale and the Autism-Spectrum Quotient (AQ), respectively. The differences in the scores of ISMI and AQ according to patient characteristics were investigated. Multiple regression analysis controlling for age and gender was performed to determine the relationship between the total scores on the AQ and IMSI scale. Results: Female patients showed a higher level of self-stigma than males. Unmarried patients showed a significantly higher score on the AQ than married patients. Multiple regression analysis adjusted for age and gender indicated that the total score on AQ might be a predictor of the overall rating on ISMI in patients with schizophrenia spectrum disorders. Conclusion: This study is the first to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Our results highlight the importance of considering autistic symptoms in the assessment and management of self-stigma in patients with schizophrenia spectrum disorders.

Original language	English
Pages (from-to)	2553-2561
Number of pages	9
Journal	Neuropsychiatric Disease and Treatment
Volume	16
DOIs	https://doi.org/10.2147/NDT.S280485
Publication status	Published - 2020

Keywords

Autistic symptoms
Gender difference
Marital status
Schizophrenia spectrum disorders
Self-stigma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2147/NDT.S280485

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Komatsu, H., Ono, T., Maita, Y., Ishida, Y., Kikuchi, T., Maki, T., Hase, S., Sakurai, H., Oba, A., Teshirogi, O., Suzuki, A., Mori, Y., Shoji, C., Fujita, A., Takahashi, S., Ebina, T., Ozaki, S., Honma, R., Tomita, H., & Kakuto, Y. (2020). Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Neuropsychiatric Disease and Treatment, 16, 2553-2561. https://doi.org/10.2147/NDT.S280485

@article{118630e14cd04c81ba8399e28c0d39b9,

title = "Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders",

abstract = "Purpose: Self-stigma negatively influences self-esteem, quality of life, self-efficacy, treatment adherence, and recovery in psychiatric patients. By revealing personality traits that influence self-stigma, we can gain useful knowledge for the management of self-stigma. A previous meta-analysis indicated that patients with schizophrenia have higher scores on the Autism-Spectrum Quotient (AQ) than healthy controls. However, the relationship between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders remains unclear. Therefore, the present study aimed to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Patients and Methods: We recruited 127 patients with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, and delusional disorder). We assessed participants{\textquoteright} self-stigma and autistic symptoms using the Internalized Stigma for Mental Illness (ISMI) scale and the Autism-Spectrum Quotient (AQ), respectively. The differences in the scores of ISMI and AQ according to patient characteristics were investigated. Multiple regression analysis controlling for age and gender was performed to determine the relationship between the total scores on the AQ and IMSI scale. Results: Female patients showed a higher level of self-stigma than males. Unmarried patients showed a significantly higher score on the AQ than married patients. Multiple regression analysis adjusted for age and gender indicated that the total score on AQ might be a predictor of the overall rating on ISMI in patients with schizophrenia spectrum disorders. Conclusion: This study is the first to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Our results highlight the importance of considering autistic symptoms in the assessment and management of self-stigma in patients with schizophrenia spectrum disorders.",

keywords = "Autistic symptoms, Gender difference, Marital status, Schizophrenia spectrum disorders, Self-stigma",

author = "Hiroshi Komatsu and Takashi Ono and Yoshinori Maita and Yusuke Ishida and Tatsuo Kikuchi and Takahiro Maki and Satoshi Hase and Hisakazu Sakurai and Akiko Oba and Osamu Teshirogi and Akira Suzuki and Yasuko Mori and Chikako Shoji and Akira Fujita and Sachiko Takahashi and Takayuki Ebina and Shinya Ozaki and Ryuta Honma and Hiroaki Tomita and Yoshihisa Kakuto",

note = "Publisher Copyright: {\textcopyright} 2020 Komatsu et al.",

year = "2020",

doi = "10.2147/NDT.S280485",

language = "English",

volume = "16",

pages = "2553--2561",

journal = "Neuropsychiatric Disease and Treatment",

issn = "1178-2021",

publisher = "Dove Medical Press Ltd.",

}

Komatsu, H, Ono, T, Maita, Y, Ishida, Y, Kikuchi, T, Maki, T, Hase, S, Sakurai, H, Oba, A, Teshirogi, O, Suzuki, A, Mori, Y, Shoji, C, Fujita, A, Takahashi, S, Ebina, T, Ozaki, S, Honma, R, Tomita, H & Kakuto, Y 2020, 'Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders', Neuropsychiatric Disease and Treatment, vol. 16, pp. 2553-2561. https://doi.org/10.2147/NDT.S280485

TY - JOUR

T1 - Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders

AU - Komatsu, Hiroshi

AU - Ono, Takashi

AU - Maita, Yoshinori

AU - Ishida, Yusuke

AU - Kikuchi, Tatsuo

AU - Maki, Takahiro

AU - Hase, Satoshi

AU - Sakurai, Hisakazu

AU - Oba, Akiko

AU - Teshirogi, Osamu

AU - Suzuki, Akira

AU - Mori, Yasuko

AU - Shoji, Chikako

AU - Fujita, Akira

AU - Takahashi, Sachiko

AU - Ebina, Takayuki

AU - Ozaki, Shinya

AU - Honma, Ryuta

AU - Tomita, Hiroaki

AU - Kakuto, Yoshihisa

PY - 2020

Y1 - 2020

N2 - Purpose: Self-stigma negatively influences self-esteem, quality of life, self-efficacy, treatment adherence, and recovery in psychiatric patients. By revealing personality traits that influence self-stigma, we can gain useful knowledge for the management of self-stigma. A previous meta-analysis indicated that patients with schizophrenia have higher scores on the Autism-Spectrum Quotient (AQ) than healthy controls. However, the relationship between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders remains unclear. Therefore, the present study aimed to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Patients and Methods: We recruited 127 patients with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, and delusional disorder). We assessed participants’ self-stigma and autistic symptoms using the Internalized Stigma for Mental Illness (ISMI) scale and the Autism-Spectrum Quotient (AQ), respectively. The differences in the scores of ISMI and AQ according to patient characteristics were investigated. Multiple regression analysis controlling for age and gender was performed to determine the relationship between the total scores on the AQ and IMSI scale. Results: Female patients showed a higher level of self-stigma than males. Unmarried patients showed a significantly higher score on the AQ than married patients. Multiple regression analysis adjusted for age and gender indicated that the total score on AQ might be a predictor of the overall rating on ISMI in patients with schizophrenia spectrum disorders. Conclusion: This study is the first to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Our results highlight the importance of considering autistic symptoms in the assessment and management of self-stigma in patients with schizophrenia spectrum disorders.

AB - Purpose: Self-stigma negatively influences self-esteem, quality of life, self-efficacy, treatment adherence, and recovery in psychiatric patients. By revealing personality traits that influence self-stigma, we can gain useful knowledge for the management of self-stigma. A previous meta-analysis indicated that patients with schizophrenia have higher scores on the Autism-Spectrum Quotient (AQ) than healthy controls. However, the relationship between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders remains unclear. Therefore, the present study aimed to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Patients and Methods: We recruited 127 patients with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, and delusional disorder). We assessed participants’ self-stigma and autistic symptoms using the Internalized Stigma for Mental Illness (ISMI) scale and the Autism-Spectrum Quotient (AQ), respectively. The differences in the scores of ISMI and AQ according to patient characteristics were investigated. Multiple regression analysis controlling for age and gender was performed to determine the relationship between the total scores on the AQ and IMSI scale. Results: Female patients showed a higher level of self-stigma than males. Unmarried patients showed a significantly higher score on the AQ than married patients. Multiple regression analysis adjusted for age and gender indicated that the total score on AQ might be a predictor of the overall rating on ISMI in patients with schizophrenia spectrum disorders. Conclusion: This study is the first to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Our results highlight the importance of considering autistic symptoms in the assessment and management of self-stigma in patients with schizophrenia spectrum disorders.

KW - Autistic symptoms

KW - Gender difference

KW - Marital status

KW - Schizophrenia spectrum disorders

KW - Self-stigma

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UR - http://www.scopus.com/inward/citedby.url?scp=85094663223&partnerID=8YFLogxK

U2 - 10.2147/NDT.S280485

DO - 10.2147/NDT.S280485

M3 - Article

AN - SCOPUS:85094663223

SN - 1178-2021

VL - 16

SP - 2553

EP - 2561

JO - Neuropsychiatric Disease and Treatment

JF - Neuropsychiatric Disease and Treatment

ER -

Association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders

Abstract

Keywords

UN SDGs

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