Asymmetric total synthesis of martinelline and martinellic acid

Shuhei Ikeda; Masatoshi Shibuya; Yoshiharu Iwabuchi

doi:10.1039/b611121a

Asymmetric total synthesis of martinelline and martinellic acid

Shuhei Ikeda, Masatoshi Shibuya, Yoshiharu Iwabuchi

PHA - Molecular Pharmaceutical Science

Tohoku University

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

Abstract

Herein, we describe the first asymmetric total synthesis of (-)-martinelline ((-)-2) and the second total synthesis of (-)-martinellic acid ((-)-1) by employing a tandem Mukaiyama-Mannich reaction/aminal cyclization as the key step.

Original language	English
Pages (from-to)	504-506
Number of pages	3
Journal	Chemical Communications
Issue number	5
DOIs	https://doi.org/10.1039/b611121a
Publication status	Published - 2007

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10.1039/b611121a

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title = "Asymmetric total synthesis of martinelline and martinellic acid",

abstract = "Herein, we describe the first asymmetric total synthesis of (-)-martinelline ((-)-2) and the second total synthesis of (-)-martinellic acid ((-)-1) by employing a tandem Mukaiyama-Mannich reaction/aminal cyclization as the key step.",

author = "Shuhei Ikeda and Masatoshi Shibuya and Yoshiharu Iwabuchi",

year = "2007",

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AU - Ikeda, Shuhei

AU - Shibuya, Masatoshi

AU - Iwabuchi, Yoshiharu

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AB - Herein, we describe the first asymmetric total synthesis of (-)-martinelline ((-)-2) and the second total synthesis of (-)-martinellic acid ((-)-1) by employing a tandem Mukaiyama-Mannich reaction/aminal cyclization as the key step.

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JO - Chemical Communications

JF - Chemical Communications

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Asymmetric total synthesis of martinelline and martinellic acid

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