Attempt at standardization of bone quantitative ultrasound in Japan

Takahiko Otani, Masao Fukunaga, Kosei Yho, Takami Miki, Kaoru Yamazaki, Hideaki Kishimoto, Mami Matsukawa, Nobuyuki Endoh, Hiroyuki Hachiya, Hiroshi Kanai, Saeko Fujiwara, Yoshinori Nagai

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


Dual X-ray absorptiometry (DXA) is used to diagnose osteoporosis. On the other hand, quantitative ultrasound (QUS) is widely used to assess bone density as part of medical screening as it is relatively inexpensive and easy to perform. Current QUS devices do not share precise ultrasound-related parameters, such as frequency, waveform, beam pattern, transient response, definition of propagation time, definition of degree of attenuation, and precise measurement site, resulting in different measurements across models. The Japan Osteoporosis Society established a QUS Standardization Committee in 2007 to investigate standardization of speed of sound (SOS) and broadband ultrasonic attenuation (BUA) measurements to resolve this issue. The committee came up with a formula to convert SOS and BUA values yielded by each model available in Japan. This has made it possible to convert QUS measurements from different models into standardized values, greatly improving the effectiveness of QUS measurements.

Original languageEnglish
Pages (from-to)3-13
Number of pages11
JournalJournal of medical ultrasonics (2001)
Issue number1
Publication statusPublished - 2018 Jan 1


  • Broadband ultrasonic attenuation (BUA)
  • Quantitative ultrasound (QUS)
  • Speed of sound (SOS)
  • Standardization of QUS


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