Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss

Yoshitaka Takanashi; Tatsuro Misu; Kazuha Oda; Hiromitsu Miyazaki; Izumi Yahata; Hiroshi Hidaka; Kazuo Fujihara; Tetsuaki Kawase; Toshimitsu Kobayashi; Yukio Katori

doi:10.1016/j.jocn.2014.04.019

Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss

Yoshitaka Takanashi, Tatsuro Misu, Kazuha Oda, Hiromitsu Miyazaki, Izumi Yahata, Hiroshi Hidaka, Kazuo Fujihara, Tetsuaki Kawase, Toshimitsu Kobayashi, Yukio Katori

Tohoku University

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Neuromyelitis optica (NMO) is an autoimmune astrocytopathy caused by anti-aquaporin 4 antibody. Only two patients with NMO have been reported presenting with hearing disorders to our knowledge. We recently treated a 40-year-old woman with NMO complaining of right hearing loss. Audiometry showed minimal asymmetry, but the auditory brainstem responses (ABR) were severely attenuated on the right. The attenuated ABR and her aural symptoms (hearing loss and fullness) improved after steroid treatment. The present case shows that the retrocochlear-type hearing loss may be associated with NMO.

Original language	English
Pages (from-to)	2249-2251
Number of pages	3
Journal	Journal of Clinical Neuroscience
Volume	21
Issue number	12
DOIs	https://doi.org/10.1016/j.jocn.2014.04.019
Publication status	Published - 2014 Dec

Keywords

Auditory brainstem response
Multiple sclerosis
Neuromyelitis optica

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10.1016/j.jocn.2014.04.019

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title = "Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss",

abstract = "Neuromyelitis optica (NMO) is an autoimmune astrocytopathy caused by anti-aquaporin 4 antibody. Only two patients with NMO have been reported presenting with hearing disorders to our knowledge. We recently treated a 40-year-old woman with NMO complaining of right hearing loss. Audiometry showed minimal asymmetry, but the auditory brainstem responses (ABR) were severely attenuated on the right. The attenuated ABR and her aural symptoms (hearing loss and fullness) improved after steroid treatment. The present case shows that the retrocochlear-type hearing loss may be associated with NMO.",

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author = "Yoshitaka Takanashi and Tatsuro Misu and Kazuha Oda and Hiromitsu Miyazaki and Izumi Yahata and Hiroshi Hidaka and Kazuo Fujihara and Tetsuaki Kawase and Toshimitsu Kobayashi and Yukio Katori",

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AU - Takanashi, Yoshitaka

AU - Misu, Tatsuro

AU - Oda, Kazuha

AU - Miyazaki, Hiromitsu

AU - Yahata, Izumi

AU - Hidaka, Hiroshi

AU - Fujihara, Kazuo

AU - Kawase, Tetsuaki

AU - Kobayashi, Toshimitsu

AU - Katori, Yukio

PY - 2014/12

Y1 - 2014/12

N2 - Neuromyelitis optica (NMO) is an autoimmune astrocytopathy caused by anti-aquaporin 4 antibody. Only two patients with NMO have been reported presenting with hearing disorders to our knowledge. We recently treated a 40-year-old woman with NMO complaining of right hearing loss. Audiometry showed minimal asymmetry, but the auditory brainstem responses (ABR) were severely attenuated on the right. The attenuated ABR and her aural symptoms (hearing loss and fullness) improved after steroid treatment. The present case shows that the retrocochlear-type hearing loss may be associated with NMO.

AB - Neuromyelitis optica (NMO) is an autoimmune astrocytopathy caused by anti-aquaporin 4 antibody. Only two patients with NMO have been reported presenting with hearing disorders to our knowledge. We recently treated a 40-year-old woman with NMO complaining of right hearing loss. Audiometry showed minimal asymmetry, but the auditory brainstem responses (ABR) were severely attenuated on the right. The attenuated ABR and her aural symptoms (hearing loss and fullness) improved after steroid treatment. The present case shows that the retrocochlear-type hearing loss may be associated with NMO.

KW - Auditory brainstem response

KW - Multiple sclerosis

KW - Neuromyelitis optica

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Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss

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Keywords

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