Abstract
Neuromyelitis optica was previously considered a subtype of multiple sclerosis until a specific serum antibody, NMO-IgG, was discovered in 2004. In 2012, anti-MOG antibody was found specifically in the serum of patients whose presentation was similar to those with neuromyelitis optica. These autoantibodies are pathogenic and are important disease markers when reaching a diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | 297-304 |
| Number of pages | 8 |
| Journal | Brain and Nerve |
| Volume | 70 |
| Issue number | 4 |
| Publication status | Published - 2018 Apr |
Keywords
- Aquaporin-4
- Auto-antibody
- Multiple sclerosis
- Myelin oligodendrocyte glycoprotein
- Neuromyelitis optica