TY - JOUR
T1 - Beating Heart Cardioscopy
T2 - A Platform for Real-Time, Intracardiac Imaging
AU - Mihaljevic, Tomislav
AU - Ootaki, Yoshio
AU - Robertson, Jason O.
AU - Durrani, Amir K.
AU - Kamohara, Keiji
AU - Akiyama, Masatoshi
AU - Cingoz, Faruk
AU - Ootaki, Chiyo
AU - Dessoffy, Raymond
AU - Kopcak, Michael
AU - Liu, Jenny
AU - Fukamachi, Kiyotaka
N1 - Funding Information:
The authors independently developed this technology and had full control of the design of the study, methods used, outcome measurements, and production of the written report. This work was supported by a grant from the United States Army Telemedicine and Advanced Technologies Research Center.
PY - 2008/3
Y1 - 2008/3
N2 - Purpose: The purpose of this study was to develop a method for real-time, fiberoptic, intracardiac imaging to serve as a platform for closed-chest, intracardiac surgery on the beating heart. Description: Fiberoptic cardioscopy of the left and right heart was conducted in a porcine model. A cardiopulmonary bypass circuit maintained systemic organ perfusion and a separate circuit replaced intracardiac blood with oxygenated, modified Krebs-Henseleit perfusate. Evaluation: Video images of structures in the left and right sides of an in vivo beating heart were obtained, including the inner surface of the left and right atria and ventricles, the mitral and aortic valves, the Thebesian veins, and the coronary sinus. Effective isolation of the heart from systemic and intracardiac blood flow and control of perfusion rates were important factors for successful image acquisition. Conclusions: Fiberoptic cardioscopy is a novel approach that allows for visualization of the structures within a nonarrested heart on bypass. It lays the groundwork for a platform that could lead to more successful percutaneous valvular and intracardiac procedures in a stable hemodynamic environment.
AB - Purpose: The purpose of this study was to develop a method for real-time, fiberoptic, intracardiac imaging to serve as a platform for closed-chest, intracardiac surgery on the beating heart. Description: Fiberoptic cardioscopy of the left and right heart was conducted in a porcine model. A cardiopulmonary bypass circuit maintained systemic organ perfusion and a separate circuit replaced intracardiac blood with oxygenated, modified Krebs-Henseleit perfusate. Evaluation: Video images of structures in the left and right sides of an in vivo beating heart were obtained, including the inner surface of the left and right atria and ventricles, the mitral and aortic valves, the Thebesian veins, and the coronary sinus. Effective isolation of the heart from systemic and intracardiac blood flow and control of perfusion rates were important factors for successful image acquisition. Conclusions: Fiberoptic cardioscopy is a novel approach that allows for visualization of the structures within a nonarrested heart on bypass. It lays the groundwork for a platform that could lead to more successful percutaneous valvular and intracardiac procedures in a stable hemodynamic environment.
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U2 - 10.1016/j.athoracsur.2007.09.037
DO - 10.1016/j.athoracsur.2007.09.037
M3 - Article
C2 - 18291198
AN - SCOPUS:39149119278
SN - 0003-4975
VL - 85
SP - 1061
EP - 1065
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 3
ER -