TY - JOUR
T1 - Biology and genome of a newly discovered sibling species of Caenorhabditis elegans
AU - Kanzaki, Natsumi
AU - Tsai, Isheng J.
AU - Tanaka, Ryusei
AU - Hunt, Vicky L.
AU - Liu, Dang
AU - Tsuyama, Kenji
AU - Maeda, Yasunobu
AU - Namai, Satoshi
AU - Kumagai, Ryohei
AU - Tracey, Alan
AU - Holroyd, Nancy
AU - Doyle, Stephen R.
AU - Woodruff, Gavin C.
AU - Murase, Kazunori
AU - Kitazume, Hiromi
AU - Chai, Cynthia
AU - Akagi, Allison
AU - Panda, Oishika
AU - Ke, Huei Mien
AU - Schroeder, Frank C.
AU - Wang, John
AU - Berriman, Matthew
AU - Sternberg, Paul W.
AU - Sugimoto, Asako
AU - Kikuchi, Taisei
N1 - Funding Information:
This work was supported by Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Numbers 26292178, 16H04722, and 15K14503. V.L.H. was supported by JSPS International Research Fellowship, A.T., N.H., S.R.D., and M.B. by the core funding at the Wellcome Trust Sanger Institute (grant no. 206194), P.W.S. by Howard Hughes Medical Institute. Genome data analyses were partly performed using the DDBJ supercomputer system. We thank Akemi Yoshida, Mark Bligh, Mohammad-Masum Billah, Tanzila Afrin, Aya Adachi, Shakhinur Islam Mondal, Arzuba Akter, Haruhiko Maruyama, Tzu-hao Kuo, Karen Brooks, Michelle Smith for assistance and comments.
Publisher Copyright:
© 2018, The Author(s).
PY - 2018/12/1
Y1 - 2018/12/1
N2 - A ‘sibling’ species of the model organism Caenorhabditis elegans has long been sought for use in comparative analyses that would enable deep evolutionary interpretations of biological phenomena. Here, we describe the first sibling species of C. elegans, C. inopinata n. sp., isolated from fig syconia in Okinawa, Japan. We investigate the morphology, developmental processes and behaviour of C. inopinata, which differ significantly from those of C. elegans. The 123-Mb C. inopinata genome was sequenced and assembled into six nuclear chromosomes, allowing delineation of Caenorhabditis genome evolution and revealing unique characteristics, such as highly expanded transposable elements that might have contributed to the genome evolution of C. inopinata. In addition, C. inopinata exhibits massive gene losses in chemoreceptor gene families, which could be correlated with its limited habitat area. We have developed genetic and molecular techniques for C. inopinata; thus C. inopinata provides an exciting new platform for comparative evolutionary studies.
AB - A ‘sibling’ species of the model organism Caenorhabditis elegans has long been sought for use in comparative analyses that would enable deep evolutionary interpretations of biological phenomena. Here, we describe the first sibling species of C. elegans, C. inopinata n. sp., isolated from fig syconia in Okinawa, Japan. We investigate the morphology, developmental processes and behaviour of C. inopinata, which differ significantly from those of C. elegans. The 123-Mb C. inopinata genome was sequenced and assembled into six nuclear chromosomes, allowing delineation of Caenorhabditis genome evolution and revealing unique characteristics, such as highly expanded transposable elements that might have contributed to the genome evolution of C. inopinata. In addition, C. inopinata exhibits massive gene losses in chemoreceptor gene families, which could be correlated with its limited habitat area. We have developed genetic and molecular techniques for C. inopinata; thus C. inopinata provides an exciting new platform for comparative evolutionary studies.
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U2 - 10.1038/s41467-018-05712-5
DO - 10.1038/s41467-018-05712-5
M3 - Article
C2 - 30097582
AN - SCOPUS:85051478357
SN - 2041-1723
VL - 9
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 3216
ER -