Blood flow analysis in carotid artery bifurcation by two-dimensional ultrasonic-measurement-integrated simulation

Hiroko Kadowaki, Toshiyuki Hayase, Kenichi Funamoto, Shusaku Sone, Tadashi Shimazaki, Takao Jibiki, Koji Miyama

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


If highly precise elucidation of the blood flow characteristics in a carotid bifurcation was possible, it would be widely applicable to diagnosis of circulatory diseases such as arteriosclerosis and cerebrovascular disease. This study was conducted to establish a new flow-dividing ratio estimation method applicable to an unsteady flow on a two-dimensional ultrasonic-measurement-integrated simulation of a carotid artery bifurcation for which it has been previously difficult to obtain a stable solution. In this new method, the flow-dividing ratio was directly adjusted by specifying the flow rate in a branch so that the difference of the Doppler velocities in the external carotid artery was decreased. The effectiveness of the proposed method was confirmed by a numerical experiment using the actual shape of a carotid artery bifurcation, and the superiority of the two-dimensional ultrasonic-measurement-integrated simulation over the ordinary simulation in terms of the reproducibility of the blood flow structure was clarified by analysis using clinical ultrasound data.

Original languageEnglish
Pages (from-to)1-14
Number of pages14
JournalJournal of Biomechanical Science and Engineering
Issue number1
Publication statusPublished - 2015


  • Arteriosclerosis
  • Bifurcation
  • Carotid artery
  • Hemodynamics
  • Ultrasonic-measurement-integrated simulation


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