TY - GEN
T1 - Both pneumatic and magnetic induction of scattered cells on micro channel array for cellular analysis
AU - Hiranishi, T.
AU - Tonomura, W.
AU - Ino, K.
AU - Okochi, M.
AU - Honda, H.
AU - Konishi, S.
PY - 2008
Y1 - 2008
N2 - Patch clamp method for cellular analysis uses pneumatic suction force to induce and clamp a cell. "Micro channel array" (hereafter MCA) integrated with micro channels and electrodes for electrophysiological bio-sensing have been studied in order to apply MEMS technology to cellular analysis. This paper presents integration of magnetic induction to MCA in addition to pneumatic induction. Magnetite cationic liposomes (MCLs) are used to magnetically label the target cells. Electroplated structures into micro channels as magnetic paths can induce magnetic flux generated behind MCA substrate. Induced magnetic flux at individual micro channels can attract magnetically labeled cells so as to allocate and clamp scattered cells on MCA. Magnetic induction allows pneumatic micro channel to be diverted to other purposes such as chemical delivery for photodynamic cell perforation. MCA equipped with magnetic induction is demonstrated in this study.
AB - Patch clamp method for cellular analysis uses pneumatic suction force to induce and clamp a cell. "Micro channel array" (hereafter MCA) integrated with micro channels and electrodes for electrophysiological bio-sensing have been studied in order to apply MEMS technology to cellular analysis. This paper presents integration of magnetic induction to MCA in addition to pneumatic induction. Magnetite cationic liposomes (MCLs) are used to magnetically label the target cells. Electroplated structures into micro channels as magnetic paths can induce magnetic flux generated behind MCA substrate. Induced magnetic flux at individual micro channels can attract magnetically labeled cells so as to allocate and clamp scattered cells on MCA. Magnetic induction allows pneumatic micro channel to be diverted to other purposes such as chemical delivery for photodynamic cell perforation. MCA equipped with magnetic induction is demonstrated in this study.
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U2 - 10.1109/MEMSYS.2008.4443648
DO - 10.1109/MEMSYS.2008.4443648
M3 - Conference contribution
AN - SCOPUS:50149103241
SN - 9781424417933
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 284
EP - 287
BT - MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
T2 - 21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
Y2 - 13 January 2008 through 17 January 2008
ER -