Cardiac Purkinje cells

Penelope A. Boyden; Masanori Hirose; Wen Dun

doi:10.1016/j.hrthm.2009.09.017

Cardiac Purkinje cells

Penelope A. Boyden, Masanori Hirose, Wen Dun

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling. This review touches on each of these points as we outline what is known today about Purkinje fibers/cells.

Original language	English
Pages (from-to)	127-135
Number of pages	9
Journal	Heart Rhythm
Volume	7
Issue number	1
DOIs	https://doi.org/10.1016/j.hrthm.2009.09.017
Publication status	Published - 2010 Jan

Keywords

Arrhythmia
Calcium
Ion channel
Pacemaker activity
Purkinje cell

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.hrthm.2009.09.017

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AB - Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling. This review touches on each of these points as we outline what is known today about Purkinje fibers/cells.

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KW - Calcium

KW - Ion channel

KW - Pacemaker activity

KW - Purkinje cell

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Cardiac Purkinje cells

Abstract

Keywords

ASJC Scopus subject areas

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