Carolacton possessing biofilm-controlling properties; Total synthesis, truncated analog synthesis, and biological phenomenon

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Abstract

Carolacton (1) was isolated from the culture broth of Sorangium cellulosum strain So ce960 and possesses 12-membered macrocyclic lactone with an aliphatic chain bearing a carboxy group at terminal. It exhibits reduction of the number of viable cells in biofilms. In this review, total synthesis, truncated analog synthesis, and biological phenomenon of 1 are described.

Original languageEnglish
Pages (from-to)1292-1293
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume75
Issue number12
DOIs
Publication statusPublished - 2017

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