Cation-π interaction between the trimethylammonium moiety and the aromatic ring within lndole-3-acetic acid choline ester, a model compound for molecular recognition between acetylcholine and its esterase: An X-ray study

Katsuyuki Aoki, Kazutaka Murayama, Hisao Nishiyama

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

X-Ray analysis of indole-3-acetic acid choline ester, a model compound for molecular recognition between the neurotransmitter acetylcholine and its esterase, shows that the quaternary trimethylammonium group is folded back to make a close contact with the indole ring through the cation-π interaction; 1H NMR spectroscopy confirms this type of interaction also occurs in solution.

Original languageEnglish
Pages (from-to)2221-2222
Number of pages2
JournalChemical Communications
Issue number21
DOIs
Publication statusPublished - 1995

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