CFTR and bicarbonate secretion to epithelial cells

Martin J. Hug, Tsutomu Tamada, Robert J. Bridges

Research output: Contribution to journalArticlepeer-review

73 Citations (Scopus)


Defective HCO3- and fluid secretion are hallmarks of the pathophysiology of the pancreas of cystic fibrosis patients. Recently, impaired HCO3- secretion has been shown in most tissues known to express the cystic fibrosis transmembrane conductance regulator (CFTR). New results suggest that CFTR plays an important role in the transcellular secretion of HCO3-.

Original languageEnglish
Pages (from-to)38-42
Number of pages5
JournalNews in Physiological Sciences
Issue number1
Publication statusPublished - 2003 Feb
Externally publishedYes

ASJC Scopus subject areas

  • Physiology


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