Defective HCO3- and fluid secretion are hallmarks of the pathophysiology of the pancreas of cystic fibrosis patients. Recently, impaired HCO3- secretion has been shown in most tissues known to express the cystic fibrosis transmembrane conductance regulator (CFTR). New results suggest that CFTR plays an important role in the transcellular secretion of HCO3-.
|Number of pages||5|
|Journal||News in Physiological Sciences|
|Publication status||Published - 2003 Feb|
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