CFTR and bicarbonate secretion to epithelial cells

Martin J. Hug; Tsutomu Tamada; Robert J. Bridges

doi:10.1152/nips.01412.2002

CFTR and bicarbonate secretion to epithelial cells

Martin J. Hug, Tsutomu Tamada, Robert J. Bridges

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

Defective HCO₃^- and fluid secretion are hallmarks of the pathophysiology of the pancreas of cystic fibrosis patients. Recently, impaired HCO₃^- secretion has been shown in most tissues known to express the cystic fibrosis transmembrane conductance regulator (CFTR). New results suggest that CFTR plays an important role in the transcellular secretion of HCO₃^-.

Original language	English
Pages (from-to)	38-42
Number of pages	5
Journal	News in Physiological Sciences
Volume	18
Issue number	1
DOIs	https://doi.org/10.1152/nips.01412.2002
Publication status	Published - 2003 Feb
Externally published	Yes

ASJC Scopus subject areas

Physiology

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10.1152/nips.01412.2002

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title = "CFTR and bicarbonate secretion to epithelial cells",

abstract = "Defective HCO3- and fluid secretion are hallmarks of the pathophysiology of the pancreas of cystic fibrosis patients. Recently, impaired HCO3- secretion has been shown in most tissues known to express the cystic fibrosis transmembrane conductance regulator (CFTR). New results suggest that CFTR plays an important role in the transcellular secretion of HCO3-.",

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AU - Tamada, Tsutomu

AU - Bridges, Robert J.

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AB - Defective HCO3- and fluid secretion are hallmarks of the pathophysiology of the pancreas of cystic fibrosis patients. Recently, impaired HCO3- secretion has been shown in most tissues known to express the cystic fibrosis transmembrane conductance regulator (CFTR). New results suggest that CFTR plays an important role in the transcellular secretion of HCO3-.

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VL - 18

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JO - Physiology

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CFTR and bicarbonate secretion to epithelial cells

Abstract

ASJC Scopus subject areas

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