Characterization of renal angiomyolipoma by scanning acoustic microscopy

Hidehiko Sasaki, Yoshifumi Saijo, Motonao Tanaka, Shin Ichi Nitta, Tomoyuki Yambe, Yoshio Terasawa

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


A scanning acoustic microscope system was used to differentiate renal angiomyolipoma from renal cell carcinoma. The ultrasonic frequency used ranged from 100 to 200 MHz, and the attenuation constant and sound speed were measured on a two-dimensional distribution. The sound speed was significantly lower for lipoma cells than for vessels, smooth muscle fibres, clear cell renal cancer or granular cell renal cancer. The attenuation constant was significantly lower for lipoma cells than for vessels or clear cells. Both acoustic parameters for smooth muscle fibres were significantly lower than for vessels. The heterogeneity of the microacoustic field in renal angiomyolipoma is closely related to the high intensity echo observed on clinical echography. Renal angiomyolipoma and renal cell carcinoma can thus be distinguished by acoustic examination.

Original languageEnglish
Pages (from-to)455-461
Number of pages7
JournalJournal of Pathology
Issue number4
Publication statusPublished - 1997 Apr


  • acoustic microscopy
  • attenuation constant
  • renal angiomyolipoma
  • renal cell carcinoma
  • sound speed


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