Cholangiocarcinoma arising from preexisting biliary hamartoma of liver - Report of a case

Takashi Orii, Nobuhiro Ohkohchi, Kiyoko Sasaki, Susumu Satomi, Mika Watanabe, Takuya Moriya

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


We describe the case of a 72-year-old asymptomatic man with a cholangiocarcinoma arising from a biliary hamartoma, also referred to as "von Meyenburg's complex". The patient was clinically diagnosed as having a cystadenocarcinoma, but the tumor had already been present as a uniformly low-density area on computed tomography taken four years previously, as revealed by retrospective examination of the computed tomography films that had been taken annually after surgery for pulmonary emphysema. The low-density area had continued to enlarge year after year, and a high-density area was observed to have emerged inside the low-density area on computed tomography. Histopathological examination demonstrated that the high-density area corresponded to the cholangiocarcinoma and the low-density area to a biliary hamartoma. This is the first case in which it was possible to confirm the presence of cholangiocarcinoma inside a biliary hamartoma that had continued to increase in size.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
Issue number50
Publication statusPublished - 2003 Mar


  • Biliary Hamartoma
  • Cholangiocarcinoma
  • Growth of biliary Hamartoma
  • Von Meyenburg's complex

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


Dive into the research topics of 'Cholangiocarcinoma arising from preexisting biliary hamartoma of liver - Report of a case'. Together they form a unique fingerprint.

Cite this