Chronological changes in brain MRI, SPECT, and EEG in neurosarcoidosis with stroke-like episodes

Kazunori Matsumoto, Shuichi Awata, Hiroo Matsuoka, Shozo Nakamura, Mitsumoto Sato

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Neurosarcoidosis with recurrent stroke-like episodes has been reported only rarely in the literature. We repeatedly measured brain magnetic resonance images (MRI), SPECT, and electroencephalograms (EEG) in a 32-year- old male patient with this condition. In the acute stage of the episodes, he showed semi-coma followed by severe dysphasia; left-frontal EEG delta wave activities and left-sided hyperperfusion SPECT were noted. Gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) MRI findings were aggravated diffusely in the convalescent stage of the disease rather than in the acute stage. The EEG and SPECT findings were clearly reflective of an early stage of acute encephalomeningitis caused by the neurosarcoidosis, and thus are more useful than MRI for evaluation of the acute inflammatory process in this condition.

Original languageEnglish
Pages (from-to)629-633
Number of pages5
JournalPsychiatry and Clinical Neurosciences
Issue number6
Publication statusPublished - 1998 Dec
Externally publishedYes


  • EEG
  • MRI
  • Neurosarcoidosis
  • Stroke

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health


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