TY - JOUR
T1 - Classification of types of intraductal papillary-mucinous neoplasm of the pancreas
T2 - A consensus study
AU - Furukawa, Toru
AU - Klöppel, Günter
AU - Volkan Adsay, N.
AU - Albores-Saavedra, Jorge
AU - Fukushima, Noriyoshi
AU - Horii, Akira
AU - Hruban, Ralph H.
AU - Kato, Yo
AU - Klimstra, David S.
AU - Longnecker, Daniel S.
AU - Lüttges, Jutta
AU - Offerhaus, G. Johan A.
AU - Shimizu, Michio
AU - Sunamura, Makoto
AU - Suriawinata, Arief
AU - Takaori, Kyoichi
AU - Yonezawa, Suguru
N1 - Funding Information:
This work was supported in part by a Grant-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan, the Pancreas Research Foundation of Japan, the Gonryo Medical Foundation, and NIH SPORE (Specialized Programs of Research Excellence) in Gastrointestinal Cancer Grant CA62924.
PY - 2005/11
Y1 - 2005/11
N2 - Now that more than two decades have passed since the first reports of intraductal papillary-mucinous neoplasms (IPMNs), it has become clear that IPMN consists of a spectrum of neoplasms with both morphological and immunohistochemical variations. At a meeting of international experts on pancreatic precursor lesions held in 2003, it was agreed that a consensus classification of IPMN subtypes should be established to enable a more detailed analysis of the clinicopathological significance of the variations. Based on our experience and on information from the literature, we selected representative histological examples of IPMNs and defined a consensus nomenclature and criteria for classifying variants as distinctive IPMN subtypes including gastric type, intestinal type, pancreatobiliary type, and oncocytic type. These definitions can be used for further analyses of the clinicopathological significance of the variations of IPMN.
AB - Now that more than two decades have passed since the first reports of intraductal papillary-mucinous neoplasms (IPMNs), it has become clear that IPMN consists of a spectrum of neoplasms with both morphological and immunohistochemical variations. At a meeting of international experts on pancreatic precursor lesions held in 2003, it was agreed that a consensus classification of IPMN subtypes should be established to enable a more detailed analysis of the clinicopathological significance of the variations. Based on our experience and on information from the literature, we selected representative histological examples of IPMNs and defined a consensus nomenclature and criteria for classifying variants as distinctive IPMN subtypes including gastric type, intestinal type, pancreatobiliary type, and oncocytic type. These definitions can be used for further analyses of the clinicopathological significance of the variations of IPMN.
KW - Classification
KW - Intraductal papillary-mucinous neoplasm
KW - MUC
KW - Pancreatic tumor
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U2 - 10.1007/s00428-005-0039-7
DO - 10.1007/s00428-005-0039-7
M3 - Article
C2 - 16088402
AN - SCOPUS:28444458875
SN - 0945-6317
VL - 447
SP - 794
EP - 799
JO - Virchows Archiv
JF - Virchows Archiv
IS - 5
ER -